مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

244
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

121
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

Flavonoids from Salvia chloroleuca with α-Amylsae and α-Glucosidase Inhibitory Effect

Pages

  609-615

Abstract

 It is believed that the inhibition of carbohydrate hydrolyzing enzymes including α;-amylase and α;-glucosidase is one of the therapeutic approaches to decrease the postprandial glucose level after a meal, especially in the people with type 2 diabetes. Medicinal plants and their extracts are one of the main sources to find new inhibitors to the enzymes. In our study four Flavonoids, namely luteolin 7-O-glucoside (1), luteolin 7-O-glucuronide (2), diosmetin 7-O-glucuronide (3) and salvigenin (4) were isolated from aerial parts of Salvia chloroleuca. The inhibitory activity of these compounds against α;-amylase and α;-glucosidase were evaluated. Compounds 1, 2 and 3 showed potent α;-glucosidase inhibitory effect with IC50 values of 18. 3, 14. 7, and 17. 1 μ M, respectively. Also these compounds exhibited moderate α;-amylase activity with IC50 values 81. 7, 61. 5, and 76. 3 μ M, respectively.

Cites

  • No record.
  • References

  • No record.
  • Cite

    APA: Copy

    Asghari, Behvar, SALEHI, PEYMAN, SONBOLI, ALI, & NEJAD EBRAHIMI, SAMAD. (2015). Flavonoids from Salvia chloroleuca with α-Amylsae and α-Glucosidase Inhibitory Effect. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), 14(2), 609-615. SID. https://sid.ir/paper/288448/en

    Vancouver: Copy

    Asghari Behvar, SALEHI PEYMAN, SONBOLI ALI, NEJAD EBRAHIMI SAMAD. Flavonoids from Salvia chloroleuca with α-Amylsae and α-Glucosidase Inhibitory Effect. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR)[Internet]. 2015;14(2):609-615. Available from: https://sid.ir/paper/288448/en

    IEEE: Copy

    Behvar Asghari, PEYMAN SALEHI, ALI SONBOLI, and SAMAD NEJAD EBRAHIMI, “Flavonoids from Salvia chloroleuca with α-Amylsae and α-Glucosidase Inhibitory Effect,” IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), vol. 14, no. 2, pp. 609–615, 2015, [Online]. Available: https://sid.ir/paper/288448/en

    Related Journal Papers

  • No record.
  • Related Seminar Papers

  • No record.
  • Related Plans

  • No record.
  • Recommended Workshops






    Move to top
    telegram sharing button
    whatsapp sharing button
    linkedin sharing button
    twitter sharing button
    email sharing button
    email sharing button
    email sharing button
    sharethis sharing button