DYNAMIC GROWTH OF AMASTIGOTES OF LEISHMANIA MAJOR AND LEISHMANIA TROPICA IN HUMAN MACROPHAGES

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

KHEYR ANDISH GHADIMI KHEYR ELAH NEZHAD F.; MOHEBALI M.; ESLAMI ZIA; RAHIMI A.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: HAKIM RESEARCH JOURNAL Year:2002 | Volume:5 | Issue:2 Page(s): 127-132

Download Full-Text

Persian Verion

View:

890

Download:

Cites:

Information Journal Paper

Title

DYNAMIC GROWTH OF AMASTIGOTES OF LEISHMANIA MAJOR AND LEISHMANIA TROPICA IN HUMAN MACROPHAGES

Author(s)

KHEYR ANDISH GHADIMI KHEYR ELAH NEZHAD F. | MOHEBALI M. | ESLAMI ZIA | RAHIMI A. | Issue Writer Certificate

Keywords

AMASTIGOTEQ4

LEISHMANIAQ4

HUMANQ4

MACROPHAGEQ4

Abstract

This study has been carried out on mononuclear cells of peripheral blood to identify that L.major and L.tropica parasites have life cycle inside MACROPHAGE similar to the host. The in-vitro dynamic proliferation of the obligate intracellular protozoan parasites of L.tropica and L.major on peripheral mononuclear cells of five groups was investigated as follows: 1- control group(ten individuals) 2- Infected with L.tropica and sensitive to the treatment(five individuals) 3- Infected with L.major and sensitive to the treatment(five individuals) 4- Infected with L.tropica and resistant to the treatment (five individuals) 5- Infected with L.major and resistant to treatment (five individuals). Separated mononuclear cells of peripheral blood were infected with L.major and L.tropica and they were cultivated for 14 days. In the days 1, 3, 5, 7, 10, 14 after infection, the number of infected MACROPHAGEs and the number of amastigots/macrophage have been counted.Using statistical trials t.test and paired t.test, no significant differences observed between two healty groups. On the other hand, significant differences observed between resistant and control groups as well as sensitive and resistant groups (P<0.05). Severe infection with L.major and L.tropica in both resistant groups has been shown in this study.The identification of the dynamic of proliferative cycle of L.tropica and L.major in HUMAN MACROPHAGEs can help us for successful treatment of cutaneous leismaniasis.

Cites

No record.

References

No record.

Cite

APA: Copy

KHEYR ANDISH GHADIMI KHEYR ELAH NEZHAD, F., MOHEBALI, M., ESLAMI, ZIA, & RAHIMI, A.. (2002). DYNAMIC GROWTH OF AMASTIGOTES OF LEISHMANIA MAJOR AND LEISHMANIA TROPICA IN HUMAN MACROPHAGES. HAKIM RESEARCH JOURNAL, 5(2), 127-132. SID. https://sid.ir/paper/29139/en

Vancouver: Copy

KHEYR ANDISH GHADIMI KHEYR ELAH NEZHAD F., MOHEBALI M., ESLAMI ZIA, RAHIMI A.. DYNAMIC GROWTH OF AMASTIGOTES OF LEISHMANIA MAJOR AND LEISHMANIA TROPICA IN HUMAN MACROPHAGES. HAKIM RESEARCH JOURNAL[Internet]. 2002;5(2):127-132. Available from: https://sid.ir/paper/29139/en

IEEE: Copy

F. KHEYR ANDISH GHADIMI KHEYR ELAH NEZHAD, M. MOHEBALI, ZIA ESLAMI, and A. RAHIMI, “DYNAMIC GROWTH OF AMASTIGOTES OF LEISHMANIA MAJOR AND LEISHMANIA TROPICA IN HUMAN MACROPHAGES,” HAKIM RESEARCH JOURNAL, vol. 5, no. 2, pp. 127–132, 2002, [Online]. Available: https://sid.ir/paper/29139/en

Related Journal Papers