مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

302
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

125
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

COMBINED α-THALASSEMIA AND HEMOGLOBIN J-IRAN (β77 HIS → ASP): A FAMILY STUDY IN SOUTHERN IRAN

Pages

  586-589

Abstract

 We report the case of a 23-year-old man and 3 members of his family with HB J-IRAN confirmed by ELECTROPHORESIS, chain separation by high-performance liquid CHROMATOGRAPHY, and sequencing. Alpha thalassemia was also confirmed in two family members. The substitution at b 77 leads to a higher negative charge of the b J-Iran subunit, which enhances its electrostatic attraction for the normally positively charged a subunit.Therefore, more HB J-IRAN than Hb A forms in the red blood cells of heterozygotes. In a -thalassemia, the more attractive b J-Iran subunit out-competes b A subunits in forming assemblies with deficient a subunits, so even more HB J-IRAN is formed.

Cites

  • No record.
  • References

  • No record.
  • Cite

    APA: Copy

    DEHGHANI, S.J., AMIRI DASHTARZHEN, A., NASIRABADI, SH., DEHBOZORGIAN, J., AFRASIABI, A.R., MORSHEDI, N., IMANIFARD, J., MEHRPOOR, SH., GERDABI, J., & KARIMI, M.. (2011). COMBINED α-THALASSEMIA AND HEMOGLOBIN J-IRAN (β77 HIS → ASP): A FAMILY STUDY IN SOUTHERN IRAN. IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), 13(8), 586-589. SID. https://sid.ir/paper/292383/en

    Vancouver: Copy

    DEHGHANI S.J., AMIRI DASHTARZHEN A., NASIRABADI SH., DEHBOZORGIAN J., AFRASIABI A.R., MORSHEDI N., IMANIFARD J., MEHRPOOR SH., GERDABI J., KARIMI M.. COMBINED α-THALASSEMIA AND HEMOGLOBIN J-IRAN (β77 HIS → ASP): A FAMILY STUDY IN SOUTHERN IRAN. IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ)[Internet]. 2011;13(8):586-589. Available from: https://sid.ir/paper/292383/en

    IEEE: Copy

    S.J. DEHGHANI, A. AMIRI DASHTARZHEN, SH. NASIRABADI, J. DEHBOZORGIAN, A.R. AFRASIABI, N. MORSHEDI, J. IMANIFARD, SH. MEHRPOOR, J. GERDABI, and M. KARIMI, “COMBINED α-THALASSEMIA AND HEMOGLOBIN J-IRAN (β77 HIS → ASP): A FAMILY STUDY IN SOUTHERN IRAN,” IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), vol. 13, no. 8, pp. 586–589, 2011, [Online]. Available: https://sid.ir/paper/292383/en

    Related Journal Papers

  • No record.
  • Related Seminar Papers

  • No record.
  • Related Plans

  • No record.
  • Recommended Workshops






    Move to top
    telegram sharing button
    whatsapp sharing button
    linkedin sharing button
    twitter sharing button
    email sharing button
    email sharing button
    email sharing button
    sharethis sharing button