PROTECTIVE EFFECTS OF METFORMIN ON RENAL TUBULAR CELLS (LETTER)

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RAFIEIAN KOPAEI MAHMOUD; BARADARAN AZAR

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

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Journal: Iranian Red Crescent Medical Journal Year:2014 | Volume:16 | Issue:9 Page(s): 1-2

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Title

PROTECTIVE EFFECTS OF METFORMIN ON RENAL TUBULAR CELLS (LETTER)

Author(s)

RAFIEIAN KOPAEI MAHMOUD | BARADARAN AZAR | Issue Writer Certificate

Keywords

METFORMIN

KIDNEY

TOXICITY

Abstract

Dear Editor; Recently, we conducted a preclinical investigation to find the ameliorative properties of METFORMIN on renal biochemical and histologic alterations of gentamicin-induced KIDNEY damage in male Wistar rats (1). In this investigation, attenuation of gentamicin-induced acute KIDNEY injury was found. Likewise, Taheri et al. conducted a study on the effects of METFORMIN on renal tubular cells after unilateral ischemia reperfusion in rats’ KIDNEY. They observed that METFORMIN provided KIDNEY protection against ischemia and reperfusion-induced injury (2). They concluded that METFORMIN has tissue-protective effect through activation of adenosine monophosphate-activated protein kinase (AMPK) and endothelial nitric oxide synthase (2). More recently we conducted a study on 70 male Wistar rats to test the efficacy of coadministrating garlic extract and METFORMIN in prevention of gentamicin-induced renal tubular damage in Wistar rats (3). The result of this study showed that METFORMIN, garlic juice, or their combination had both curative and protective effects on gentamicin-induced KIDNEY injury. In addition, Kim et al...

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APA: Copy

RAFIEIAN KOPAEI, MAHMOUD, & BARADARAN, AZAR. (2014). PROTECTIVE EFFECTS OF METFORMIN ON RENAL TUBULAR CELLS (LETTER). IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), 16(9), 1-2. SID. https://sid.ir/paper/292670/en

Vancouver: Copy

RAFIEIAN KOPAEI MAHMOUD, BARADARAN AZAR. PROTECTIVE EFFECTS OF METFORMIN ON RENAL TUBULAR CELLS (LETTER). IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ)[Internet]. 2014;16(9):1-2. Available from: https://sid.ir/paper/292670/en

IEEE: Copy

MAHMOUD RAFIEIAN KOPAEI, and AZAR BARADARAN, “PROTECTIVE EFFECTS OF METFORMIN ON RENAL TUBULAR CELLS (LETTER),” IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), vol. 16, no. 9, pp. 1–2, 2014, [Online]. Available: https://sid.ir/paper/292670/en

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