HER2 ILE655VAL SINGLE NUCLEOTIDE POLYMORPHISM IN PATIENTS WITH OVARIAN CANCER

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MOJTAHEDI ZAHRA; ERFANI NASROOLAH; MALEKZADEH MAHYAR; HAGHSHENAS MOHAMMAD REZA; GHADERI ABBAS; SAMSAMI DEHAGHANI ALAMTAJ

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Journal Paper

Paper Information

Journal: Iranian Red Crescent Medical Journal Year:2013 | Volume:15 | Issue:1 Page(s): 1-3

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Information Journal Paper

Title

HER2 ILE655VAL SINGLE NUCLEOTIDE POLYMORPHISM IN PATIENTS WITH OVARIAN CANCER

Author(s)

Keywords

CARCINOMA

ENDOMETRIOID

HER2

POLYMORPHISM

SINGLE NUCLEOTIDE

Abstract

Background: The association between HER2 Ile655Val SINGLE NUCLEOTIDE POLYMORPHISM and cancer is controversial.Objectives: The aim of our study was to investigate this POLYMORPHISM in patients with ovarian cancer.Patients and Methods: Genomic DNA was extracted from peripheral blood leukocytes of 107 patients and 130 healthy women. HER2 gene POLYMORPHISM was assessed by PCR-RFLP.Results: No significant difference was observed in genotype and allele frequency between patient and control groups according to HER2 Ile655Val POLYMORPHISM. The disease stage, age, and histological type were also not associated with the POLYMORPHISM.Conclusions: our data showed that HER2 Ile655Val SINGLE NUCLEOTIDE POLYMORPHISM was not significantly associated with onset, histological type, age, and stage of ovarian cancer in Iranian patients.

Cites

ROLE OF HER-2 ILE655VAL POLYMORPHISM AS UNIVERSAL CANCER SUSCEPTIBILITY MARKER AMONG DIFFERENT CANCERS

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APA: Copy

MOJTAHEDI, ZAHRA, ERFANI, NASROOLAH, MALEKZADEH, MAHYAR, HAGHSHENAS, MOHAMMAD REZA, GHADERI, ABBAS, & SAMSAMI DEHAGHANI, ALAMTAJ. (2013). HER2 ILE655VAL SINGLE NUCLEOTIDE POLYMORPHISM IN PATIENTS WITH OVARIAN CANCER. IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), 15(1), 1-3. SID. https://sid.ir/paper/292767/en

Vancouver: Copy

MOJTAHEDI ZAHRA, ERFANI NASROOLAH, MALEKZADEH MAHYAR, HAGHSHENAS MOHAMMAD REZA, GHADERI ABBAS, SAMSAMI DEHAGHANI ALAMTAJ. HER2 ILE655VAL SINGLE NUCLEOTIDE POLYMORPHISM IN PATIENTS WITH OVARIAN CANCER. IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ)[Internet]. 2013;15(1):1-3. Available from: https://sid.ir/paper/292767/en

IEEE: Copy

ZAHRA MOJTAHEDI, NASROOLAH ERFANI, MAHYAR MALEKZADEH, MOHAMMAD REZA HAGHSHENAS, ABBAS GHADERI, and ALAMTAJ SAMSAMI DEHAGHANI, “HER2 ILE655VAL SINGLE NUCLEOTIDE POLYMORPHISM IN PATIENTS WITH OVARIAN CANCER,” IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), vol. 15, no. 1, pp. 1–3, 2013, [Online]. Available: https://sid.ir/paper/292767/en

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