INCIDENCE AND CLINICAL COURSE OF PATENT DUCTUS ARTERIOSUS IN PREMATURE NEONATES ADMITTED IN NEONATAL ICU WARD, NEMAZEE HOSPITAL

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POUR ARIAN SH.

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Journal: HAKIM RESEARCH JOURNAL Year:2003 | Volume:6 | Issue:3 Page(s): 77-81

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Title

INCIDENCE AND CLINICAL COURSE OF PATENT DUCTUS ARTERIOSUS IN PREMATURE NEONATES ADMITTED IN NEONATAL ICU WARD, NEMAZEE HOSPITAL

Author(s)

POUR ARIAN SH. | Issue Writer Certificate

Keywords

PATENT DUCTUS ARTERIOSUS- PREMATURE INFANTQ4

Abstract

Introduction: The advance in survival of premature neonates has significantly increased the incidence of patent ductus arteriosus (PDA). The pharmacological closure of the duct by antiprostoglandins has changed the clinical course of PDA. Early diagnosis and management of PDA can prevent many foreseeable complications. The objectives of this study were to determine the incidence, clinical profile and outcome of PDA in premature infants. Methods: In this study, seventeen neonates admitted over a one year period from September 2000 to November 2001 to the NICU at Nemazee Hospital of Shiraz University of Medical Sciences, were diagnosed as cases with PDA. The epidemiologic and clinical profile, management and outcome of PDA were investigated by a cross-sectional design. Echocardiography was used to confirm the clinically suspected PDA and repeated to demonstrate the closure of PDA.Results: PDA occurred in 14.9% of the total 114 premature infants who were admitted to NICU. The analysis revealed that respiratory distress syndrome (RDS) and pneumonia were the most determinant factors in 12 cases (70.6%) and sepsis in 3 (17.6%). More than three-fourth of the neonates had an onset of PDA in the first week of life accompanied by an inverse relation to birth weight and gestational age. The major presenting features were systolic murmur (100%), bounding pulses (30%) and tachycardia (47%). About 82.3% of the neonates responded to oral ibuprofen with no complications. Conclusion: Detection of abnormal heart sounds can be the best guide for early diagnosis of PDA especially in premature infants with RDS. Using echocardiography for confirmation of diagnosis and initiation of antiprostaglandins is crucial in preventing any complications in these patients.

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APA: Copy

POUR ARIAN, SH.. (2003). INCIDENCE AND CLINICAL COURSE OF PATENT DUCTUS ARTERIOSUS IN PREMATURE NEONATES ADMITTED IN NEONATAL ICU WARD, NEMAZEE HOSPITAL. HAKIM RESEARCH JOURNAL, 6(3), 77-81. SID. https://sid.ir/paper/29328/en

Vancouver: Copy

POUR ARIAN SH.. INCIDENCE AND CLINICAL COURSE OF PATENT DUCTUS ARTERIOSUS IN PREMATURE NEONATES ADMITTED IN NEONATAL ICU WARD, NEMAZEE HOSPITAL. HAKIM RESEARCH JOURNAL[Internet]. 2003;6(3):77-81. Available from: https://sid.ir/paper/29328/en

IEEE: Copy

SH. POUR ARIAN, “INCIDENCE AND CLINICAL COURSE OF PATENT DUCTUS ARTERIOSUS IN PREMATURE NEONATES ADMITTED IN NEONATAL ICU WARD, NEMAZEE HOSPITAL,” HAKIM RESEARCH JOURNAL, vol. 6, no. 3, pp. 77–81, 2003, [Online]. Available: https://sid.ir/paper/29328/en

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