Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

821
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

552
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

2

Information Journal Paper

Title

EFFECT OF WITHANIA SOMNIFERA ON LEVELS OF SEX HORMONES IN THE DIABETIC MALE RATS

Pages

  163-168

Abstract

 Background: There are evidences regarding the prevalence of dysfunction in sexual function and behavior in diabetic people. Experimental studies revealed a positive effect of WITHANIA SOMNIFERA on sexual function and behaviors.Objective: In this research, the effect of WITHANIA SOMNIFERA on sexual function in diabetic male Wistar RATs was assessed by measuring the serum levels of testosterone, progesterone, estrogen, FSH and LH.Materials and Methods: Experimental DIABETES mellitus type I was induced by intraperitoneal injection of a single dose (60 mg/kg) of streptozotocin (STZ) in Wistar male RATs. Oral WITHANIA SOMNIFERA root was given in pelleted food at RATio of 6.25% for 4 weeks. The levels of gonadadotropic hormones (LH, FSH), progesterone, estrogen and testosterone in animals’ serum were determined after 4 weeks in all groups. Results: WITHANIA SOMNIFERA root was effective in lowering FSH serum level in somnifera-treated animals compared to controls (p<0.05) in both diabetic and non-diabetic groups, whereas progesterone (p<0.05), testosterone (p<0.05) and LH levels (p<0.001) were significantly higher in non-diabetic treated animals. Oral somnifera root was also able to reverse the reductive effect of DIABETES on the progesterone. The estrogen level did not show any significant difference in any of the groups.Conclusion: It is suggested that WITHANIA SOMNIFERA may have a regulatory effect on DIABETES-induced change of the levels of gonadal-hormones, especially progesterone, in male RATs. Nevertheless, somnifera is apparently only able to diminish FSH serum level in intact animals.  

Cites

References

  • No record.

    • Cite

    APA: Copy

    KIASALARI, Z., KHALILI, MOHSEN, & AGHAEI, MAHBOUBEH. (2009). EFFECT OF WITHANIA SOMNIFERA ON LEVELS OF SEX HORMONES IN THE DIABETIC MALE RATS. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), 7(4), 163-168. SID. https://sid.ir/paper/295464/en

    Vancouver: Copy

    KIASALARI Z., KHALILI MOHSEN, AGHAEI MAHBOUBEH. EFFECT OF WITHANIA SOMNIFERA ON LEVELS OF SEX HORMONES IN THE DIABETIC MALE RATS. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE)[Internet]. 2009;7(4):163-168. Available from: https://sid.ir/paper/295464/en

    IEEE: Copy

    Z. KIASALARI, MOHSEN KHALILI, and MAHBOUBEH AGHAEI, “EFFECT OF WITHANIA SOMNIFERA ON LEVELS OF SEX HORMONES IN THE DIABETIC MALE RATS,” INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), vol. 7, no. 4, pp. 163–168, 2009, [Online]. Available: https://sid.ir/paper/295464/en

    Related Journal Papers

  • No record.

    • Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops






    Move to top