مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Information Journal Paper

Title

THE IMPACT OF ALPHA LIPOIC ACID ON DEVELOPMENTAL COMPETENCE OF MOUSE VITRIFIED PRE-ANTRAL FOLLICLES IN COMPARISON TO THOSE ISOLATED FROM VITRIFIED OVARIES

Pages

  57-64

Abstract

 Background: Cryopreservation of ovarian tissues and pre-antral follicles is a promising prospect for preservation of women fertility.Objective: The aim of this study was to evaluate the in vitro developmental competence of mouse vitrified pre-antral follicles in comparison to isolated pre-antral follicles derived from vitrified ovaries in the presence of ALPHA LIPOIC ACID (ALA).Materials and Methods: Pre-antral follicles derived from fresh, vitrified-warmed ovarian tissues and vitrified–warmed pre-antral follicles were cultured individually with or without ALA, followed by adding hCG to induce ovulation. The follicle growth, oocyte maturation, and embryo development were assessed.Results: The diameter and development of follicles, oocyte maturation and embryo development rates were significantly higher in ALA supplemented groups compared to the respective ALA-free conditions groups. Aforementioned parameters were significantly higher in vitrified-warmed follicles in comparison to follicles derived from vitrified-warmed ovaries.Conclusion: These findings support a superior performance of pre-antral follicles when vitrified rather than when isolated from vitrified ovaries with regard to increasing the rates of developmental parameters. Moreover, ALA improves the in vitro maturation of pre-antral follicles in vitrified and non-vitrified samples.

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    APA: Copy

    HATAMI, SAHAR, ZAVAREH, SAEED, SALEHNIA, MOJDEH, LASHKARBOLOUKI, TAGHI, GHORBANIAN, MOHAMMAD TAGHI, & KARIMI, ISAAC. (2014). THE IMPACT OF ALPHA LIPOIC ACID ON DEVELOPMENTAL COMPETENCE OF MOUSE VITRIFIED PRE-ANTRAL FOLLICLES IN COMPARISON TO THOSE ISOLATED FROM VITRIFIED OVARIES. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), 12(1), 57-64. SID. https://sid.ir/paper/296052/en

    Vancouver: Copy

    HATAMI SAHAR, ZAVAREH SAEED, SALEHNIA MOJDEH, LASHKARBOLOUKI TAGHI, GHORBANIAN MOHAMMAD TAGHI, KARIMI ISAAC. THE IMPACT OF ALPHA LIPOIC ACID ON DEVELOPMENTAL COMPETENCE OF MOUSE VITRIFIED PRE-ANTRAL FOLLICLES IN COMPARISON TO THOSE ISOLATED FROM VITRIFIED OVARIES. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE)[Internet]. 2014;12(1):57-64. Available from: https://sid.ir/paper/296052/en

    IEEE: Copy

    SAHAR HATAMI, SAEED ZAVAREH, MOJDEH SALEHNIA, TAGHI LASHKARBOLOUKI, MOHAMMAD TAGHI GHORBANIAN, and ISAAC KARIMI, “THE IMPACT OF ALPHA LIPOIC ACID ON DEVELOPMENTAL COMPETENCE OF MOUSE VITRIFIED PRE-ANTRAL FOLLICLES IN COMPARISON TO THOSE ISOLATED FROM VITRIFIED OVARIES,” INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), vol. 12, no. 1, pp. 57–64, 2014, [Online]. Available: https://sid.ir/paper/296052/en

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