Evaluation of Ibuprofen Release from Gelatin /Hydroxyapatite /Polylactic Acid Nanocomposites

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Nabipour Zohre; NOURBAKHSH MOHAMMAD SADEGH; BANIASADI MOHAMMAD

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: IRANIAN JOURNAL OF PHARMACEUTICAL SCIENCES Year:2018 | Volume:14 | Issue:1 Page(s): 75-84

Download Full-Text

View:

200

Download:

Cites:

Information Journal Paper

Title

Evaluation of Ibuprofen Release from Gelatin /Hydroxyapatite /Polylactic Acid Nanocomposites

Author(s)

Nabipour Zohre | NOURBAKHSH MOHAMMAD SADEGH | BANIASADI MOHAMMAD | Issue Writer Certificate

Keywords

Nanocomposites

Hydroxyapatite

Polylactic acid

Ibuprofen

Release profile

Drug delivery

Abstract

Gelatin-Hydroxyapatite-Polylactic acid (PLA) Nanocomposites were synthesized using five different formulations. The Nanocomposites were loaded with Ibuprofen and the amount of drug in the carriers was determined. X-ray diffraction (XRD) analysis was conducted before and after drug loading to ensure the presence of Ibuprofen on the Nanocomposites. Drug delivery was evaluated in phosphate buffered saline (PBS) solution at pH 7. 4 and 37° C. The results of XRD analysis showed acceptable synthesis of Hydroxyapatite and the composites, confirming the loading of Ibuprofen onto the synthesized nanocarriers. The results showed that maximum drug loading (58. 2%) was recorded for sample D (30% gelatin, 40% nHA and 30% PLA), and minimum loading was recorded for sample E (30% gelatin, 30% nHA and 40% PLA). The maximum percentage of drug release over the course of 72 h (95. 8%) was for nanocomposite D (30% gelatin, 40% nHA and 30% PLA). The minimum percentage of Drug delivery (77%) was for nanocomposite E (30% gelatin, 30% nHA, 40% PLA), which contained the maximum PLA content.

Cites

No record.

References

SYNTHESIS, CHARACTERIZATION AND BIOCOMPATIBILITY EVALUATION OF HYDROXYAPATITE - GELATIN POLYLACTIC ACID TERNARY NANOCOMPOSITE

Cite

APA: Copy

Nabipour, Zohre, NOURBAKHSH, MOHAMMAD SADEGH, & BANIASADI, MOHAMMAD. (2018). Evaluation of Ibuprofen Release from Gelatin /Hydroxyapatite /Polylactic Acid Nanocomposites. IRANIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 14(1), 75-84. SID. https://sid.ir/paper/300384/en

Vancouver: Copy

Nabipour Zohre, NOURBAKHSH MOHAMMAD SADEGH, BANIASADI MOHAMMAD. Evaluation of Ibuprofen Release from Gelatin /Hydroxyapatite /Polylactic Acid Nanocomposites. IRANIAN JOURNAL OF PHARMACEUTICAL SCIENCES[Internet]. 2018;14(1):75-84. Available from: https://sid.ir/paper/300384/en

IEEE: Copy

Zohre Nabipour, MOHAMMAD SADEGH NOURBAKHSH, and MOHAMMAD BANIASADI, “Evaluation of Ibuprofen Release from Gelatin /Hydroxyapatite /Polylactic Acid Nanocomposites,” IRANIAN JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 14, no. 1, pp. 75–84, 2018, [Online]. Available: https://sid.ir/paper/300384/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops