TRANEXAMIC ACID–A RECIPE FOR SAVING LIVES IN TRAUMATIC BLEEDING

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ROBERTS IAN

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Journal Paper

Paper Information

Journal: THE JOURNAL OF TEHRAN UNIVERSITY HEART CENTER Year:2011 | Volume:6 | Issue:4 Page(s): 178-178

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Title

TRANEXAMIC ACID–A RECIPE FOR SAVING LIVES IN TRAUMATIC BLEEDING

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ROBERTS IAN | Issue Writer Certificate

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Abstract

Using kitchen scales, carefully weight out 4 kilograms of rice and pour it into a deep saucepan. Now put your hands into the rice and let the grains run between your fingers.Contemplate carefully each grain. The number of grains (about 140,000) is approximately the number of lives that could be saved each year world-wide if all hospitalized trauma patients with significant bleeding were treated with tranexamic acid (TXA) within 3 hours of injury. TXA is cheap and widely available. All that is needed to reap these human benefits is that doctors use it.That TXA is a potent inhibitor of fibrinolysis was first reported by Shosuke and Utako Okamoto in The Keio Journal of Medicine in September 1962.Since then TXA has been widely used to treat heavy menstrual bleeding and to reduce blood loss in elective surgery where it reduces blood transfusion by about one third.2 The CRASH-2 collaborators hypothesized that TXA might also reduce bleeding in trauma patients. The CRASH-2 trial was a UK government funded randomized trial of the effects of the early administration of TXA on death, vascular occlusive events and blood transfusion in bleeding trauma patients.

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APA: Copy

ROBERTS, IAN. (2011). TRANEXAMIC ACID–A RECIPE FOR SAVING LIVES IN TRAUMATIC BLEEDING. THE JOURNAL OF TEHRAN UNIVERSITY HEART CENTER, 6(4), 178-178. SID. https://sid.ir/paper/302020/en

Vancouver: Copy

ROBERTS IAN. TRANEXAMIC ACID–A RECIPE FOR SAVING LIVES IN TRAUMATIC BLEEDING. THE JOURNAL OF TEHRAN UNIVERSITY HEART CENTER[Internet]. 2011;6(4):178-178. Available from: https://sid.ir/paper/302020/en

IEEE: Copy

IAN ROBERTS, “TRANEXAMIC ACID–A RECIPE FOR SAVING LIVES IN TRAUMATIC BLEEDING,” THE JOURNAL OF TEHRAN UNIVERSITY HEART CENTER, vol. 6, no. 4, pp. 178–178, 2011, [Online]. Available: https://sid.ir/paper/302020/en

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