Cytotoxicity of Two Experimental Epoxy Resin-Based Sealers

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ASHRAF HENGAMEH; NAJAFI FARHOOD; HEIDARI SOOLMAZ; Yadegary Zahra; ZADSIRJAN SAEEDE

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Journal Paper

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Journal: Iranian Endodontic Journal Year:2018 | Volume:13 | Issue:2 Page(s): 257-262

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Title

Cytotoxicity of Two Experimental Epoxy Resin-Based Sealers

Author(s)

Keywords

Cytotoxicity

Endodontics

Epoxy Resin

Sealer

Abstract

Introduction: Many endodontic Sealers are available, but search for the ideal Sealer continues. This study aimed to assess the Cytotoxicity of two experimental endodontic Sealers in comparison with AH-26 resin Sealer. Methods and Materials: This in vitro study was conducted on conventional and experimental root canal Sealers: AH-26, an Epoxy Resin experimental Sealer A (ES-A) composed of calcium tungstate, zirconium oxide, aerosil, bismuth oxide, titanium oxide, hexamine and an Epoxy Resin and experimental Sealer B (ES-B) with compositions similar to ES-A except for the presence of imidazoline as a catalyst. The experimental Sealers containing nano-particles were mixed with 37. 5% of an Epoxy Resin. The extraction of five samples of each experimental Sealer (A, B) and AH-26 Sealer were subjected to MTT assay in the form of set and fresh at 1, 24 and 72 h with 1, 10, 100% dilution according to the International Standard ISO: 10993-2012. Data were analyzed using the one-way ANOVA. Results: The set ES-A had the least Cytotoxicity from the first hour but the Cytotoxicity of ES-B and AH-26 extraction decreased over time. In fresh form, except for 100% concentration, ESA showed the least Cytotoxicity compared to the other two Sealers. Conclusion: All three Sealers had high Cytotoxicity in 100% concentration but had low Cytotoxicity in 10% and 1% concentrations.

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APA: Copy

ASHRAF, HENGAMEH, NAJAFI, FARHOOD, HEIDARI, SOOLMAZ, Yadegary, Zahra, & ZADSIRJAN, SAEEDE. (2018). Cytotoxicity of Two Experimental Epoxy Resin-Based Sealers. IRANIAN ENDODONTIC JOURNAL (IEJ), 13(2), 257-262. SID. https://sid.ir/paper/303053/en

Vancouver: Copy

ASHRAF HENGAMEH, NAJAFI FARHOOD, HEIDARI SOOLMAZ, Yadegary Zahra, ZADSIRJAN SAEEDE. Cytotoxicity of Two Experimental Epoxy Resin-Based Sealers. IRANIAN ENDODONTIC JOURNAL (IEJ)[Internet]. 2018;13(2):257-262. Available from: https://sid.ir/paper/303053/en

IEEE: Copy

HENGAMEH ASHRAF, FARHOOD NAJAFI, SOOLMAZ HEIDARI, Zahra Yadegary, and SAEEDE ZADSIRJAN, “Cytotoxicity of Two Experimental Epoxy Resin-Based Sealers,” IRANIAN ENDODONTIC JOURNAL (IEJ), vol. 13, no. 2, pp. 257–262, 2018, [Online]. Available: https://sid.ir/paper/303053/en

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