NEUROLOGICAL AND OTHER MANIFESTATIONS OF WILSON DISEASE; 1998-2005

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FALAH AZAR

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Journal Paper

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Journal: Iranian Journal of Child Neurology Year:2009 | Volume:3 | Issue:1 Page(s): 35-41

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Title

NEUROLOGICAL AND OTHER MANIFESTATIONS OF WILSON DISEASE; 1998-2005

Author(s)

FALAH AZAR | Issue Writer Certificate

Keywords

WILSON DISEASE

KAYSER-FLEISCHER RING

CERULOPLASMIN

Abstract

Objective: WILSON DISEASE (WD) is an inherited copper metabolism dysfunction disease characterized by cirrhosis and CNS findings. WILSON DISEASE is important because it is fatal not recognized and treated. Our Goa of study is to investigate the clinical signs and symptoms, lab results and other relevant matters in our patients in order to obtain a better understanding of this potentially lethal disease in our country.Materials & Methods: We have evaluated 21 cases of children with WILSON DISEASE who were referred to Loghman and Imam Hussein Hospital between years 1998-2005. The mean age of our patients was 9 years.Results: The presenting symptom was ascites and extremity edema in 6(28.5%) patients, behavioral changes or neurological signs in 5(24%) simultaneous Ascites and icter in 9(43%) patients and in one patient the presenting manifestation was hemolytic anemia (4.8%). One of our patients died because of fulminant hepatitis in the course of admission (4.8%).Conclusion: We showed in this study that WILSON DISEASE can be presented by a manifold symptom in children and adolescence. Having a good concept of these symptoms in high clinical suspicious are required to diagnose this potentially lethal disease at the proper time in order to decrease the potential adverse effects of the disease especially the neuropsychiatric damages significantly.

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APA: Copy

FALAH, AZAR. (2009). NEUROLOGICAL AND OTHER MANIFESTATIONS OF WILSON DISEASE; 1998-2005. IRANIAN JOURNAL OF CHILD NEUROLOGY (IJCN), 3(1), 35-41. SID. https://sid.ir/paper/303232/en

Vancouver: Copy

FALAH AZAR. NEUROLOGICAL AND OTHER MANIFESTATIONS OF WILSON DISEASE; 1998-2005. IRANIAN JOURNAL OF CHILD NEUROLOGY (IJCN)[Internet]. 2009;3(1):35-41. Available from: https://sid.ir/paper/303232/en

IEEE: Copy

AZAR FALAH, “NEUROLOGICAL AND OTHER MANIFESTATIONS OF WILSON DISEASE; 1998-2005,” IRANIAN JOURNAL OF CHILD NEUROLOGY (IJCN), vol. 3, no. 1, pp. 35–41, 2009, [Online]. Available: https://sid.ir/paper/303232/en

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