مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Information Journal Paper

Title

PROTECTIVE EFFECT OF MELATONIN AGAINST INEQUALITY-INDUCED DAMAGES ON TESTICULAR TISSUE AND SPERM PARAMETERS

Pages

  313-322

Abstract

 Background: The goals of the study are evaluation the effects of FOOD DEPRIVATION and ISOLATION SITUATION as a social stress on fertility, and in the following, investigation of the improving effect of MELATONIN as an antioxidant component.Materials and Methods: In this experimental study, We investigated histopathological and serological effects of MELATONIN and social stress (food deprivation and isolation) on different features of sperm and testicular tissue among 42 male rats in 7 groups including control, sham, MELATONIN received (M), FOOD DEPRIVATION (FD), FOOD DEPRIVATION and MELATONIN treatment (FDM), FOOD DEPRIVATION and ISOLATION SITUATION (FDi), and FOOD DEPRIVATION and MELATONIN treatment and ISOLATION SITUATION (FDMi) groups. Epididymal sperms of all rats were also counted. Histopathological evaluation of the testes was done under a light microscopy to determine the number of spermiogenic cells. Serological evaluation of testosterone, corticosterone, and MELATONIN was performed, as well. For statistical analysis, one-way ANOVA and Tukey's post hoc test were used, and the value of p≤0.05 was considered statistically significance.Results: The result showed that FOOD DEPRIVATION increased the number of abnormal, immotile, and dead sperms, while decreased the number of normal sperms (p<0.05). Isolation could improve sperm motility and viability, while enhanced the number of spermatogenic cells. MELATONIN had a protective effect on sperm count, motility, and viability, while reduced sperm abnormality.Conclusion: Our results demonstrated that MELATONIN treatment and ISOLATION SITUATION improve the parameters related to epididymal sperms and spermatogenic cells after FOOD DEPRIVATION.

Cites

References

Cite

APA: Copy

NASIRAEI MOGHADAM, SHIVA, PARIVAR, KAZEM, AHMADIANI, ABOLHASAN, MOVAHHEDIN, MANSOUREH, & VAEZ MAHDAVI, MOHAMMAD REZA. (2014). PROTECTIVE EFFECT OF MELATONIN AGAINST INEQUALITY-INDUCED DAMAGES ON TESTICULAR TISSUE AND SPERM PARAMETERS. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, 7(4), 313-322. SID. https://sid.ir/paper/305432/en

Vancouver: Copy

NASIRAEI MOGHADAM SHIVA, PARIVAR KAZEM, AHMADIANI ABOLHASAN, MOVAHHEDIN MANSOUREH, VAEZ MAHDAVI MOHAMMAD REZA. PROTECTIVE EFFECT OF MELATONIN AGAINST INEQUALITY-INDUCED DAMAGES ON TESTICULAR TISSUE AND SPERM PARAMETERS. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY[Internet]. 2014;7(4):313-322. Available from: https://sid.ir/paper/305432/en

IEEE: Copy

SHIVA NASIRAEI MOGHADAM, KAZEM PARIVAR, ABOLHASAN AHMADIANI, MANSOUREH MOVAHHEDIN, and MOHAMMAD REZA VAEZ MAHDAVI, “PROTECTIVE EFFECT OF MELATONIN AGAINST INEQUALITY-INDUCED DAMAGES ON TESTICULAR TISSUE AND SPERM PARAMETERS,” INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, vol. 7, no. 4, pp. 313–322, 2014, [Online]. Available: https://sid.ir/paper/305432/en

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