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Information Journal Paper

Title

EFFECT OF WITHANIA SOMNIFERA (L.) DUNAL ON SEX HORMONE AND GONADOTROPIN LEVELS IN ADDICTED MALE RATS

Author(s)

 RAHMATI BATOOL | GHOSIAN MOGHADDAM MOHAMMAD HASSAN | KHALILI MOHSEN | ENAYATI EHSAN | MALEKI MARYAM | REZAEEI SAEEDEH | Issue Writer Certificate 

Pages

  239-244

Abstract

 Background: Opioid consumption has been widely increasing across the globe; however, it can cause adverse effects on the body. MORPHINE, an opioid, can reduce sex hormones and fertility. WITHANIA SOMNIFERA (WS) is a traditional herb used to improve sexual activities. This study strives to investigate the effect of WS on sex hormones and GONADOTROPINS in addicted male rats.Materials and Methods: In this experimental study, forty-eight male National Maritime Research Institute (NMRI) rats were randomly divided into four groups: i. Control group, ii. WS-treated control group, iii. Addicted group, and iv. WS-treated addicted group. Water-soluble MORPHINE was given to rats for 21 days to induce addiction, concurrently the treated groups (2 and 4) also received WS plant-mixed pelleted food (6.25%). At the end of the treatment, the sex hormone and gonadotropin levels of the rats’ sera were determined in all the groups.Results: Except for follicle-stimulating hormone (FSH), MORPHINE reduced most of the gonadotropin and sex hormone levels. Whereas WS caused a considerable increase in the hormones in the treated addicted group, there was only a slight increase in the treated control group.Conclusion: WS increased sex hormones and GONADOTROPINS-especially TESTOSTERONE, ESTROGEN, and luteinizing hormone-in the addicted male rats and even increased the progesterone level, a stimulant of most sex hormones in addicted male rats.

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    APA: Copy

    RAHMATI, BATOOL, GHOSIAN MOGHADDAM, MOHAMMAD HASSAN, KHALILI, MOHSEN, ENAYATI, EHSAN, MALEKI, MARYAM, & REZAEEI, SAEEDEH. (2016). EFFECT OF WITHANIA SOMNIFERA (L.) DUNAL ON SEX HORMONE AND GONADOTROPIN LEVELS IN ADDICTED MALE RATS. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, 10(2), 239-244. SID. https://sid.ir/paper/305876/en

    Vancouver: Copy

    RAHMATI BATOOL, GHOSIAN MOGHADDAM MOHAMMAD HASSAN, KHALILI MOHSEN, ENAYATI EHSAN, MALEKI MARYAM, REZAEEI SAEEDEH. EFFECT OF WITHANIA SOMNIFERA (L.) DUNAL ON SEX HORMONE AND GONADOTROPIN LEVELS IN ADDICTED MALE RATS. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY[Internet]. 2016;10(2):239-244. Available from: https://sid.ir/paper/305876/en

    IEEE: Copy

    BATOOL RAHMATI, MOHAMMAD HASSAN GHOSIAN MOGHADDAM, MOHSEN KHALILI, EHSAN ENAYATI, MARYAM MALEKI, and SAEEDEH REZAEEI, “EFFECT OF WITHANIA SOMNIFERA (L.) DUNAL ON SEX HORMONE AND GONADOTROPIN LEVELS IN ADDICTED MALE RATS,” INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, vol. 10, no. 2, pp. 239–244, 2016, [Online]. Available: https://sid.ir/paper/305876/en

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