RESURGENCE OF MINIMAL STIMULATION IN VITRO FERTILIZATION WITH A PROTOCOL CONSISTING OF GONADOTROPIN RELEASING HORMONE-AGONIST TRIGGER AND VITRIFIED-THAWED EMBRYO TRANSFER

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ZHANG JOHN

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Journal Paper

Paper Information

Journal: International Journal of Fertility & Sterility Year:2016 | Volume:10 | Issue:2 Page(s): 148-153

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Title

RESURGENCE OF MINIMAL STIMULATION IN VITRO FERTILIZATION WITH A PROTOCOL CONSISTING OF GONADOTROPIN RELEASING HORMONE-AGONIST TRIGGER AND VITRIFIED-THAWED EMBRYO TRANSFER

Author(s)

ZHANG JOHN | Issue Writer Certificate

Keywords

IN VITRO FERTILIZATION

CLOMID

GNRH AGONIST

Abstract

Minimal stimulation IN VITRO FERTILIZATION (mini-IVF) consists of a gentle controlled ovarian stimulation that aims to produce a maximum of five to six oocytes. There is a misbelief that mini-IVF severely compromises pregnancy and live birth rates. An appraisal of the literature pertaining to studies on mini-IVF protocols was performed. The advantages of minimal stimulation protocols are reported here with a focus on the use of clomiphene citrate (CC), gonadotropin releasing hormone (GnRH) agonist trigger for oocyte maturation, and freeze-all embryo strategy. Literature review and the author’s own center data suggest that minimal ovarian stimulation protocols with GNRH AGONIST trigger and freeze-all embryo strategy along with single embryo transfer produce a reasonable clinical pregnancy and live birth rates in both good and poor responders. Additionally, mini-IVF offers numerous advantages such as: i. Reduction in cost and stress with fewer office visits, needle sticks, and ultrasounds, and ii. Reduction in the incidence of ovarian hyperstimulation syndrome (OHSS). Mini-IVF is re-emerging as a solution for some of the problems associated with conventional IVF, such as OHSS, cost, and patient discomfort.

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APA: Copy

ZHANG, JOHN. (2016). RESURGENCE OF MINIMAL STIMULATION IN VITRO FERTILIZATION WITH A PROTOCOL CONSISTING OF GONADOTROPIN RELEASING HORMONE-AGONIST TRIGGER AND VITRIFIED-THAWED EMBRYO TRANSFER. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, 10(2), 148-153. SID. https://sid.ir/paper/305882/en

Vancouver: Copy

ZHANG JOHN. RESURGENCE OF MINIMAL STIMULATION IN VITRO FERTILIZATION WITH A PROTOCOL CONSISTING OF GONADOTROPIN RELEASING HORMONE-AGONIST TRIGGER AND VITRIFIED-THAWED EMBRYO TRANSFER. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY[Internet]. 2016;10(2):148-153. Available from: https://sid.ir/paper/305882/en

IEEE: Copy

JOHN ZHANG, “RESURGENCE OF MINIMAL STIMULATION IN VITRO FERTILIZATION WITH A PROTOCOL CONSISTING OF GONADOTROPIN RELEASING HORMONE-AGONIST TRIGGER AND VITRIFIED-THAWED EMBRYO TRANSFER,” INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, vol. 10, no. 2, pp. 148–153, 2016, [Online]. Available: https://sid.ir/paper/305882/en

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