مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

321
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

203
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

CURCUMIN INHIBITS THE ADVERSE EFFECTS OF SODIUM ARSENITE IN MOUSE EPIDIDYMAL SPERM

Pages

  245-252

Abstract

 Background: The aim of this study was to investigate the effects of CURCUMIN on epididymal sperm parameters in adult male Navel Medical Research Institute (NMRI) mice exposed to SODIUM ARSENITE.Materials and Methods: In this experimental study, we divided the animals into four groups: control, SODIUM ARSENITE (5 mg/kg), CURCUMIN (100 mg/kg) and CURCUMIN+sodium arsenite. Exposures were performed by intraperitoneal injections for a 5-week period. After the exposure period, we recorded the animals’ body and left testes weights. The left caudal epididymis was used to count the sperm number and analyze motility, viability, morphological abnormalities, acrosome reaction, DNA integrity, and histone-protamine replacement in the spermatozoa. One-way analysis of variance (ANOVA) followed by the Tukey’s test was used to assess the statistical significance of the data with SPSS 16.0. P<0.05 was considered significant.Results: Mice exposed to SODIUM ARSENITE showed a significant decrease in the number, motility, viability, normal sperm morphology and acrosome integrity of spermatozoa compared to the control group. In the CURCUMIN+sodium arsenite group, CURCUMIN significantly reversed these adverse effects to the point where they approximated the control. In addition, the application of CURCUMIN alone had no significant difference in these parameters compared to the control and CURCUMIN+sodium arsenite groups. However, we observed no significant differences in the body and the testis weight as well as the DNA integrity and histone-protamine replacement in the spermatozoa of the four groups.Conclusion: CURCUMIN compensated for the toxic effects of SODIUM ARSENITE on a number of sperm parameters in adult mice.

Cites

  • No record.

    • References

  • No record.

    • Cite

    APA: Copy

    MOMENI, HAMID REZA, & ESKANDARI, NAJMEH. (2016). CURCUMIN INHIBITS THE ADVERSE EFFECTS OF SODIUM ARSENITE IN MOUSE EPIDIDYMAL SPERM. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, 10(2), 245-252. SID. https://sid.ir/paper/305886/en

    Vancouver: Copy

    MOMENI HAMID REZA, ESKANDARI NAJMEH. CURCUMIN INHIBITS THE ADVERSE EFFECTS OF SODIUM ARSENITE IN MOUSE EPIDIDYMAL SPERM. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY[Internet]. 2016;10(2):245-252. Available from: https://sid.ir/paper/305886/en

    IEEE: Copy

    HAMID REZA MOMENI, and NAJMEH ESKANDARI, “CURCUMIN INHIBITS THE ADVERSE EFFECTS OF SODIUM ARSENITE IN MOUSE EPIDIDYMAL SPERM,” INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, vol. 10, no. 2, pp. 245–252, 2016, [Online]. Available: https://sid.ir/paper/305886/en

    Related Journal Papers

  • No record.

    • Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops






    Move to top
    telegram sharing button
    whatsapp sharing button
    linkedin sharing button
    twitter sharing button
    email sharing button
    email sharing button
    email sharing button
    sharethis sharing button