THE COMPARISON BETWEEN PRAZOSIN & CLONIDINE EFFECT ON COMBAT RELATED P.T.S.D NIGHTMARES

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MOUSAVI SEYED GHAFOUR; BARATI M.; AFSHAR H.R.

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Paper Information

Journal: Daneshvar Medicine: Basic and Clinical Research Journal Year:2004 | Volume:12 | Issue:53 Page(s): 31-36

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Title

THE COMPARISON BETWEEN PRAZOSIN & CLONIDINE EFFECT ON COMBAT RELATED P.T.S.D NIGHTMARES

Author(s)

MOUSAVI SEYED GHAFOUR | BARATI M. | AFSHAR H.R. | Issue Writer Certificate

Keywords

POSTTRAUMATIC STRESS DISORDER (PTSD)Q2

NIGHTMAREQ4

PRAZOSINQ3

CLONIDINQ3

Abstract

Introduction: P. T. S. D is a psychiatric (anxiety) disorder that may develop after a catastrophic stress. One of its symptoms is NIGHTMAREs that usually is sever and impaired sleep. Some studies show increased activity of adrenergic system in this disorder. Also, some drugs such as CLONIDINe, guanfacine and PRAZOSIN that decrease the activity of this system, decrease symptoms of PTSD, such as NIGHTMAREs. In this study we compared the effects of CLONIDINe and PRAZOSIN on NIGHTMAREs of these patients. Method: On a dobule blinded clinical trial we studied two groups of inpatient PTSD by using CLONIDINe or PRAZOSIN in each group for 8 weeks. Then we rate the frequency, deepness and severity of the NIGHTMAREs. All of the patients were male, married and chronic form of disorder and those who abuser or addicted, psychotic disorders or had a medical problem for taking these drugs were not in the trial. Results: In both groups the average of NIGHTMAREs severity reduced, and they were statistically significant (P<0.001), but the difference between two groups were not statistically significant (P>0.05). Discussion: PRAZOSIN and CLONIDINe may be effective for treatment of NIGHTMAREs of PTSD patient's but there are not significant differences between them.

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References

THE EFFECT OF PRAZOSIN ON COMBAT RELATED POSTTRAUMATIC STRESS DISORDER NIGHTMARES

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APA: Copy

MOUSAVI, SEYED GHAFOUR, BARATI, M., AFSHAR, H.R.,. (2004). THE COMPARISON BETWEEN PRAZOSIN & CLONIDINE EFFECT ON COMBAT RELATED P.T.S.D NIGHTMARES. DANESHVAR MEDICINE, 12(53), 31-36. SID. https://sid.ir/paper/30711/en

Vancouver: Copy

MOUSAVI SEYED GHAFOUR, BARATI M., AFSHAR H.R.. THE COMPARISON BETWEEN PRAZOSIN & CLONIDINE EFFECT ON COMBAT RELATED P.T.S.D NIGHTMARES. DANESHVAR MEDICINE[Internet]. 2004;12(53):31-36. Available from: https://sid.ir/paper/30711/en

IEEE: Copy

SEYED GHAFOUR MOUSAVI, M. BARATI, H.R. AFSHAR, an, “THE COMPARISON BETWEEN PRAZOSIN & CLONIDINE EFFECT ON COMBAT RELATED P.T.S.D NIGHTMARES,” DANESHVAR MEDICINE, vol. 12, no. 53, pp. 31–36, 2004, [Online]. Available: https://sid.ir/paper/30711/en

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