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Information Journal Paper

Title

NEPHROQUIZ 1: CYCLOPHOSPHAMIDE OR MYCOFENOLATE MOFETIL?

Pages

  112-113

Keywords

Not Registered.

Abstract

 A 36-year-old man was admitted because of weakness, generalized edema, skin rash, and acute kidney failure with active urine sediment. Results of laboratory studies were as follows: blood leukocyte count, 14× 109/L; hemoglobin, 10 g/dL; blood platelet count, 145 × 109/L; blood urea nitrogen, 102 mg/dL; serum creatinine, 5.8 mg/dL; complement 3, 32 mg/ dL; complement 4, 3 mg/dL; serum hemolytic activity (CH50), 100 U/ mL; antinuclear antibody, 1/80; and anti-double-stranded-DNA, 1/20. On pathologic examination of the biopsy specimen from the kidney, 7 glomeruli were present, of which 1 was obsolete and others showed mesangial widening and endocapillary proliferation with neutrophilic infiltration, subendothelial hyaline deposits (wire loops), and intraluminal thrombi in some of them. Half of the glomeruli revealed cellular crescents (Figures 1 and 2). There was no spike formation. Activity index was 18/24 and chronicity index, 5/12. The fluorescent antibody technique study revealed a typically full-house pattern (Figure 3). About 40% of tubules were atrophic. Based on clinical presentation and laboratory and pathologic findings, diagnosis of diffuse proliferative lupus nephritis (class-IV-G, A/C) was established.

Cites

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    Cite

    APA: Copy

    SAMADIAN, F., PARVIN, MAHMOUD, FARAJI, A.H., & AHMADPOUR, PEDRAM. (2009). NEPHROQUIZ 1: CYCLOPHOSPHAMIDE OR MYCOFENOLATE MOFETIL?. IRANIAN JOURNAL OF KIDNEY DISEASES (IJKD), 3(2), 112-113. SID. https://sid.ir/paper/308734/en

    Vancouver: Copy

    SAMADIAN F., PARVIN MAHMOUD, FARAJI A.H., AHMADPOUR PEDRAM. NEPHROQUIZ 1: CYCLOPHOSPHAMIDE OR MYCOFENOLATE MOFETIL?. IRANIAN JOURNAL OF KIDNEY DISEASES (IJKD)[Internet]. 2009;3(2):112-113. Available from: https://sid.ir/paper/308734/en

    IEEE: Copy

    F. SAMADIAN, MAHMOUD PARVIN, A.H. FARAJI, and PEDRAM AHMADPOUR, “NEPHROQUIZ 1: CYCLOPHOSPHAMIDE OR MYCOFENOLATE MOFETIL?,” IRANIAN JOURNAL OF KIDNEY DISEASES (IJKD), vol. 3, no. 2, pp. 112–113, 2009, [Online]. Available: https://sid.ir/paper/308734/en

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