THE STUDY OF THE PREVALENCE OF HYPOTHROIDISM IN NEONATES WITH INDIRECT HYPERBILIRUBINEMIA

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AKHAVIRAD S.M.B.; RAFATI SH.; BORNA H.; ZAERI F.; SAFA BAKHSH M.

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Journal: DANESHVAR MEDICINE Year:2007 | Volume:14 | Issue:70 Page(s): 1-4

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Title

THE STUDY OF THE PREVALENCE OF HYPOTHROIDISM IN NEONATES WITH INDIRECT HYPERBILIRUBINEMIA

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Keywords

PREVALENCEQ3

NEONATESQ3

INDIRECT HYPERBILIRUBINEMIAQ3

ICTERICQ3

HYPOTHROIDISMQ4

Abstract

Introduction: Congenital hypothyroidism with PREVALENCE of 1 in every 4000 infants is of great importance, since it has irretrievable effects on brain development and IQ. Therefore, Neonatal Screening program is highly recommended, because 90% of the affected infants have no apparent symptoms and signs. However, prolongation of physiologic ICTERIC may be the earliest sign.Materials & Methods: This descriptive cross-sectional study was carried out to evaluate the PREVALENCE of hypothyroidism among 402 infants affected with indirect hyper bilirubinemia who were treated at Shahid Mostapha Khomeini hospital over a one year period. Tests on venous blood samples were performed to measure the levels of TSH & T4 after 3 days the birth TSH level>20mU/mL and T4<10mg/dL were considered as hypothyroidism. Results: Among 402 hospitalized ICTERIC infants, 51% were male and 49% female. Five males and five females (2.5%) had hypothyroidism. There were no statistically significant relationships among gender, age, weight of infant and hypothyroidism. Fisher test (DR=3.22) indicated that chance to get hypothyroidism is 3.2 times greater for those with biliurbin level>20mg/dL compared to those with bilirubin level<20mg/dL.Conclusion: Hypothyroidism among ICTERIC NEONATES has high PREVALENCE. Considering that early diagnosis and treatment can have substantially less effect on child's IQ it is recommended to mesure TSH & T4 levels 3 days after the birth for infants with bilirubin level³20mg/dL.

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APA: Copy

AKHAVIRAD, S.M.B., RAFATI, SH., BORNA, H., ZAERI, F., & SAFA BAKHSH, M.. (2007). THE STUDY OF THE PREVALENCE OF HYPOTHROIDISM IN NEONATES WITH INDIRECT HYPERBILIRUBINEMIA. DANESHVAR MEDICINE, 14(70), 1-4. SID. https://sid.ir/paper/30994/en

Vancouver: Copy

AKHAVIRAD S.M.B., RAFATI SH., BORNA H., ZAERI F., SAFA BAKHSH M.. THE STUDY OF THE PREVALENCE OF HYPOTHROIDISM IN NEONATES WITH INDIRECT HYPERBILIRUBINEMIA. DANESHVAR MEDICINE[Internet]. 2007;14(70):1-4. Available from: https://sid.ir/paper/30994/en

IEEE: Copy

S.M.B. AKHAVIRAD, SH. RAFATI, H. BORNA, F. ZAERI, and M. SAFA BAKHSH, “THE STUDY OF THE PREVALENCE OF HYPOTHROIDISM IN NEONATES WITH INDIRECT HYPERBILIRUBINEMIA,” DANESHVAR MEDICINE, vol. 14, no. 70, pp. 1–4, 2007, [Online]. Available: https://sid.ir/paper/30994/en

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