COMPARISON OF AN AEROBIC TRAINING COURSE WITH A HERBAL SUPPLEMENTATION (VALERIANA WALLICHII AND MELISSA OFFICINALIS) REGARDING SEROTONIN LEVELS, NITRIC OXIDE AND HEADACHE INDICES IN WOMEN WITH MIGRAINE

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ESKANDARI ZOHREH; MIRZAEI BAHMAN; ARAZI HAMID

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Journal: DANESHVAR MEDICINE Year:2018 | Volume:25 | Issue:135 Page(s): 51-64

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Title

COMPARISON OF AN AEROBIC TRAINING COURSE WITH A HERBAL SUPPLEMENTATION (VALERIANA WALLICHII AND MELISSA OFFICINALIS) REGARDING SEROTONIN LEVELS, NITRIC OXIDE AND HEADACHE INDICES IN WOMEN WITH MIGRAINE

Author(s)

ESKANDARI ZOHREH | MIRZAEI BAHMAN | ARAZI HAMID | Issue Writer Certificate

Keywords

MIGRAINEQ2

SEROTONINQ2

NITRIC OXIDEQ2

AEROBIC EXERCISEQ1

VALERIANA WALLICHIIQ3

MELISSA OFFICINALISQ3

Abstract

Background and Objective: MIGRAINE is a neurovascular disorder that decreases the quality of life. The purpose of this study was to evaluate the effect of aerobic training and a combination of herbal supplements includingValeriana wallichiiand MELISSA OFFICINALIS on SEROTONIN, NITRIC OXIDE and headache indices.Materials and Methods: The present study was a semi-experimental and applied research. Eighteen female patients with MIGRAINE who were eligible to participate in the study were randomly divided into two groups: aerobic training (n=9) and herbal supplements (n=9). Patients in the AEROBIC EXERCISE group performed the exercise for eight weeks, three sessions per week and each session was 75 minutes of moderate-intensity aerobic activity (15 minute warmup, 45 workouts, 15 minute cool-down). The combination of herbal supplement group received herbal capsules for eight weeks and each capsule was included 200 mg of valerian and 80 mg ofMelissa officinalis. They used it twice daily in the first four weeks and three times a day in the next four weeks. Blood samples were taken in the fasting state to determine the SEROTONIN and NITRIC OXIDE levels of the subjects before and after the intervention. Headache indexes were also assessed by a headache questionnaire. Data were analyzed by Kolmogrov-Smirnov, independent and paired T-tests and Covariance analysis at a significance level of p<0.05.Results: Results showed that in the complementary combination group, taking eight weeks of capsule significantly increased blood SEROTONIN levels and headache frequency and intensity significantly decreased. In addition, NITRIC OXIDE levels and duration of headache did not significantly differ as compared to before the study. In the aerobic training group, eight weeks of activity significantly increased SEROTONIN and NITRIC OXIDE levels and significantly decreased headache frequency and headache intensity, but did not change the duration of the headache. Also, by comparing the variables between the two groups, other than serum NITRIC OXIDE and aerobic power, the changes of the other variables were similar at the end of the study, and no significant difference was observed between them.Conclusion: Aerobic training and a combination of herbal supplements including valerian andMelissa officinalis can be a good complement therapy for women with MIGRAINE.

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APA: Copy

ESKANDARI, ZOHREH, MIRZAEI, BAHMAN, & ARAZI, HAMID. (2018). COMPARISON OF AN AEROBIC TRAINING COURSE WITH A HERBAL SUPPLEMENTATION (VALERIANA WALLICHII AND MELISSA OFFICINALIS) REGARDING SEROTONIN LEVELS, NITRIC OXIDE AND HEADACHE INDICES IN WOMEN WITH MIGRAINE. DANESHVAR MEDICINE, 25(135 ), 51-64. SID. https://sid.ir/paper/31064/en

Vancouver: Copy

ESKANDARI ZOHREH, MIRZAEI BAHMAN, ARAZI HAMID. COMPARISON OF AN AEROBIC TRAINING COURSE WITH A HERBAL SUPPLEMENTATION (VALERIANA WALLICHII AND MELISSA OFFICINALIS) REGARDING SEROTONIN LEVELS, NITRIC OXIDE AND HEADACHE INDICES IN WOMEN WITH MIGRAINE. DANESHVAR MEDICINE[Internet]. 2018;25(135 ):51-64. Available from: https://sid.ir/paper/31064/en

IEEE: Copy

ZOHREH ESKANDARI, BAHMAN MIRZAEI, and HAMID ARAZI, “COMPARISON OF AN AEROBIC TRAINING COURSE WITH A HERBAL SUPPLEMENTATION (VALERIANA WALLICHII AND MELISSA OFFICINALIS) REGARDING SEROTONIN LEVELS, NITRIC OXIDE AND HEADACHE INDICES IN WOMEN WITH MIGRAINE,” DANESHVAR MEDICINE, vol. 25, no. 135 , pp. 51–64, 2018, [Online]. Available: https://sid.ir/paper/31064/en

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