CORNEAL ENDOTHELIAL CELL DENSITY AND MORPHOLOGY FOLLOWING BOLUS VERSUS INFUSION INTRACAMERAL ADRENALINE DURING PHACOEMULSIFICATION

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ROUHANI M.R.; VAFAEI MANSOUR; IZADI SH.

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Journal: Journal of Ophthalmic and Vision Research Year:2007 | Volume:2 | Issue:2 Page(s): 124-128

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Title

CORNEAL ENDOTHELIAL CELL DENSITY AND MORPHOLOGY FOLLOWING BOLUS VERSUS INFUSION INTRACAMERAL ADRENALINE DURING PHACOEMULSIFICATION

Author(s)

ROUHANI M.R. | VAFAEI MANSOUR | IZADI SH. | Issue Writer Certificate

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Abstract

Purpose: To compare early postoperative corneal endothelial cell density and morphology after phacoemulsification using bolus versus infusion intracameral adrenaline.Methods: In this randomized clinical trial, 71 eyes of 71 patients scheduled for phacoemulsification were randomly assigned to two groups: one group (31 eyes) received bolus intracameral adrenaline (1:10,000) and the other group (30 eyes) received adrenaline infusion (1:1,000,000). Pre- and one month postoperatively, a complete ophthalmologic examination as well as endothelial evaluation using ConfoScan III was performed; effective phaco time (EPT) and mydriasis during surgery were also compared between the study groups.Results: The two study groups were not significantly different in terms of demographic characteristics, lens opacity and EPT. Endothelial cell density was 2737±321 cell/mm2 in the bolus group vs 2742±426 cell/mm2 in the infusion group preoperatively (P=0.1). One month postoperatively, the rate of cell loss was 7.21% in the infusion group versus 8.87% in the bolus group (P= 0.13). Pupil diameter was >6 mm in 48% of eyes in the infusion group vs 33% of eyes in the bolus group (P=0.5).Conclusion: Adrenaline was safe at the studied concentrations and there was no significant difference between bolus and infusion routes of administration in terms of pupil dilation and endothelial cell loss.

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References

OVERVIEW OF THE TOXICITY OF SURGICAL SOLUTIONS AND DRUGS AND CLINICAL CONCEPTS IN CORNEAL EDEMA

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APA: Copy

ROUHANI, M.R., VAFAEI, MANSOUR, & IZADI, SH.. (2007). CORNEAL ENDOTHELIAL CELL DENSITY AND MORPHOLOGY FOLLOWING BOLUS VERSUS INFUSION INTRACAMERAL ADRENALINE DURING PHACOEMULSIFICATION. JOURNAL OF OPHTHALMIC AND VISION RESEARCH, 2(2), 124-128. SID. https://sid.ir/paper/311319/en

Vancouver: Copy

ROUHANI M.R., VAFAEI MANSOUR, IZADI SH.. CORNEAL ENDOTHELIAL CELL DENSITY AND MORPHOLOGY FOLLOWING BOLUS VERSUS INFUSION INTRACAMERAL ADRENALINE DURING PHACOEMULSIFICATION. JOURNAL OF OPHTHALMIC AND VISION RESEARCH[Internet]. 2007;2(2):124-128. Available from: https://sid.ir/paper/311319/en

IEEE: Copy

M.R. ROUHANI, MANSOUR VAFAEI, and SH. IZADI, “CORNEAL ENDOTHELIAL CELL DENSITY AND MORPHOLOGY FOLLOWING BOLUS VERSUS INFUSION INTRACAMERAL ADRENALINE DURING PHACOEMULSIFICATION,” JOURNAL OF OPHTHALMIC AND VISION RESEARCH, vol. 2, no. 2, pp. 124–128, 2007, [Online]. Available: https://sid.ir/paper/311319/en

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