مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Information Journal Paper

Title

EDITORIAL; HISCOTT AND SHERIDAN: RETINAL PIGMENT EPITHELIUM DERIVED STEM CELLS

Pages

  133-133

Keywords

Not Registered.

Abstract

 Retinal pigment epithelial (RPE) stem cells offer a theoretical treatment strategy for a wide variety of retinal disorders including age-related macular degeneration (AMD) and retinal dystrophies. There are, however, a number of hurdles that will have to be overcome before a consistently reliable and successful therapy can be offered to patients. These include expansion of sufficient numbers of suitably differentiated cells for transplantation, technical issues around insertion of the cells and removal of damaged tissue (such as abnormal Bruch’s membrane in AMD), immunological rejection of transplanted cells, and control of post-transplant cell differentiation.1-3 Thus, in the case of RPE cell replacement, it may ultimately be proven that transplantation of an expanded number of differentiated cells on a porous substrate can deal with issues such as control of differentiation, prevention of proliferative vitreoretinopathy and replacement of damaged Bruch’s membrane.

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  • References

    Cite

    APA: Copy

    HISCOTT, P., & SHERIDAN, C.M.. (2009). EDITORIAL; HISCOTT AND SHERIDAN: RETINAL PIGMENT EPITHELIUM DERIVED STEM CELLS. JOURNAL OF OPHTHALMIC AND VISION RESEARCH, 4(3), 133-133. SID. https://sid.ir/paper/311371/en

    Vancouver: Copy

    HISCOTT P., SHERIDAN C.M.. EDITORIAL; HISCOTT AND SHERIDAN: RETINAL PIGMENT EPITHELIUM DERIVED STEM CELLS. JOURNAL OF OPHTHALMIC AND VISION RESEARCH[Internet]. 2009;4(3):133-133. Available from: https://sid.ir/paper/311371/en

    IEEE: Copy

    P. HISCOTT, and C.M. SHERIDAN, “EDITORIAL; HISCOTT AND SHERIDAN: RETINAL PIGMENT EPITHELIUM DERIVED STEM CELLS,” JOURNAL OF OPHTHALMIC AND VISION RESEARCH, vol. 4, no. 3, pp. 133–133, 2009, [Online]. Available: https://sid.ir/paper/311371/en

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