OSTEOPOROSIS AND OSTEOPOROTIC FRACTURES IN POSTMENOPAUSAL WOMEN WITH TYPE 2 DIABETES COMPARED WITH NON-DIABETIC CASES

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MOBINI MARYAM; KASHI ZAHRA; BAHAR ADELEH; TASLIMI FATEMEH; FORGHANIZADEH JAFAR; ABDI ROOHOLLAH

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Journal: Iranian Journal of Diabetes and Obesity Year:2012 | Volume:4 | Issue:2 Page(s): 68-73

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Title

OSTEOPOROSIS AND OSTEOPOROTIC FRACTURES IN POSTMENOPAUSAL WOMEN WITH TYPE 2 DIABETES COMPARED WITH NON-DIABETIC CASES

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Keywords

OSTEOPOROSIS

FRACTURES

TYPE 2 DIABETES

Abstract

Objective: Correlation of OSTEOPOROSIS (OP) with type 2diabetes mellitus (DM) is not as clear as type 1 DM. The purpose of this study was to compare the frequency of OP and osteoporotic FRACTURES in post- menopausal women with and without type 2 DM in Sari, Iran.Materials and Methods: Eighty post-menopausal women with type 2 DM and 80 non-diabetic controls enrolled in this study. Bone mineral density was determined with dual energy X-ray absoptiometry of L2-L4 in spine and femoral neck. Vertebral fracture was reported by a radiologist on thoraco-lumbar x ray. Hip and wrist FRACTURES were determined by patients self-report and ascertained by radiographs. T test, X2 and Fisher's exact tests were used for data analysis.Results: The mean age of diabetic women with and without OSTEOPOROSIS was 69±2.7 and 69.3±5 years, respectively (p=0.01). Diabetes duration, HbA1C and BMI were not statistically different between two groups. Diabetic complications and anti-diabetic agents, or age and duration of diabetes were not different in diabetic patients with OP or osteoporotic fracture.The mean of T-score in lumbar spine was -1.65±1.3 in diabetics and -2.11±1.3 in controls (p=0.03). T-score in femoral neck was not significantly different. In diabetic patients, the prevalence of OSTEOPOROSIS was 27.5% at lumbar spine and 17.5% at femoral neck and in controls were 46.3% and 27.5%, respectively (p=0.04 and 0.1). FRACTURES were less common in diabetics (18.8% vs. 32.5%, p=0.04).Conclusion: This study showed that OSTEOPOROSIS and osteoporotic FRACTURES is less common in post-menopausal diabetic women compared to non-diabetic subjects.

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APA: Copy

MOBINI, MARYAM, KASHI, ZAHRA, BAHAR, ADELEH, TASLIMI, FATEMEH, FORGHANIZADEH, JAFAR, & ABDI, ROOHOLLAH. (2012). OSTEOPOROSIS AND OSTEOPOROTIC FRACTURES IN POSTMENOPAUSAL WOMEN WITH TYPE 2 DIABETES COMPARED WITH NON-DIABETIC CASES. IRANIAN JOURNAL OF DIABETES AND OBESITY, 4(2), 68-73. SID. https://sid.ir/paper/318143/en

Vancouver: Copy

MOBINI MARYAM, KASHI ZAHRA, BAHAR ADELEH, TASLIMI FATEMEH, FORGHANIZADEH JAFAR, ABDI ROOHOLLAH. OSTEOPOROSIS AND OSTEOPOROTIC FRACTURES IN POSTMENOPAUSAL WOMEN WITH TYPE 2 DIABETES COMPARED WITH NON-DIABETIC CASES. IRANIAN JOURNAL OF DIABETES AND OBESITY[Internet]. 2012;4(2):68-73. Available from: https://sid.ir/paper/318143/en

IEEE: Copy

MARYAM MOBINI, ZAHRA KASHI, ADELEH BAHAR, FATEMEH TASLIMI, JAFAR FORGHANIZADEH, and ROOHOLLAH ABDI, “OSTEOPOROSIS AND OSTEOPOROTIC FRACTURES IN POSTMENOPAUSAL WOMEN WITH TYPE 2 DIABETES COMPARED WITH NON-DIABETIC CASES,” IRANIAN JOURNAL OF DIABETES AND OBESITY, vol. 4, no. 2, pp. 68–73, 2012, [Online]. Available: https://sid.ir/paper/318143/en

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