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Cites:

2

Information Journal Paper

Title

The Effect of 6 Weeks Resistance Training and HITT on GLP-1 Gene Expression of Diabetic Rats

Pages

  42-49

Keywords

HIIT (High-Intensity Interval Training) 
GLP-1R (Glucagon-Like Peptide 1-receptor) 

Abstract

 Objective: Cardiovascular diseases are the main reason of the death in Type 2 diabetic patients. The purpose of this study was to evaluate the effect of 6 weeks of Resistance training and HITT (High Intensity Interval Training) on GLP-1 gene expression in Type 2 Diabetes Mellitus. Materials and Methods: For this study, male Wistar rats of Baqiyatallah University of Medical Sciences in Tehran were used as statistical population. The statistical samples consisted of 32 male Wistar 10 weeks old weighing 220 ± 20 gr and were divided into 4 obese groups (3 diabetic Type 2 and 1 healthy groups). Groups were diabetic obstruction, resistance exercises, diabetic obesity and HITT exercises. Independent T-test and one way ANOVA were used to examine the results. Results: The results showed that the expression of GLP-1R in the left ventricle of diabetic rats was 0. 6% lower than that of the nondiabetic group, due to Type 2 diabetes induction. There was a significant difference between the groups in expressing GLP-1R in the left ventricle. The post hoc test confirmed a significant increase in the expression of GLP-1R in the resistance and Interval group compared to the control group. However, there was no significant difference in expression of GLP-1R between the two groups. Conclusion: With regard to the results of this study and other studies that have an effect on the proper administration of Glp-1 and its receptor on the heart, it can be proven to heart patients that they can recover by performing physical activity.

Cites

References

Cite

APA: Copy

Kalhor, Hossein, PEERI, MAGHSOUD, MATIN HOMAEE, HASAN, & EIZADI, MOJTABA. (2018). The Effect of 6 Weeks Resistance Training and HITT on GLP-1 Gene Expression of Diabetic Rats. IRANIAN JOURNAL OF DIABETES AND OBESITY, 10(1), 42-49. SID. https://sid.ir/paper/318218/en

Vancouver: Copy

Kalhor Hossein, PEERI MAGHSOUD, MATIN HOMAEE HASAN, EIZADI MOJTABA. The Effect of 6 Weeks Resistance Training and HITT on GLP-1 Gene Expression of Diabetic Rats. IRANIAN JOURNAL OF DIABETES AND OBESITY[Internet]. 2018;10(1):42-49. Available from: https://sid.ir/paper/318218/en

IEEE: Copy

Hossein Kalhor, MAGHSOUD PEERI, HASAN MATIN HOMAEE, and MOJTABA EIZADI, “The Effect of 6 Weeks Resistance Training and HITT on GLP-1 Gene Expression of Diabetic Rats,” IRANIAN JOURNAL OF DIABETES AND OBESITY, vol. 10, no. 1, pp. 42–49, 2018, [Online]. Available: https://sid.ir/paper/318218/en

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