مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Information Journal Paper

Title

NEW CONCEPTS ON PATHOGENESIS AND DIAGNOSIS OF LIVER FIBROSIS, A REVIEW ARTICLE

Pages

  166-178

Abstract

 Liver FIBROSIS is a potentially reversible response to hepatic insults, triggered by different chronic diseases most importantly viral hepatitis, alcoholic, and nonalcoholic fatty liver disease. In the course of the chronic liver disease, hepatic fibrogenesis may develop, which is attributed to various types of cells, molecules, and pathways. Activated hepatic stellate cell (HSC), the primary source of extracellular matrix (ECM), is fundamental in pathophysiology of fibrogenesis, and thus is the most attractable target for reversing liver FIBROSIS. Although, liver biopsy has long been considered as the gold standard for DIAGNOSIS and staging of hepatic FIBROSIS, assessing progression and regression by biopsy is hampered by its limitations. We provide recent views on noninvasive approaches including serum biomarkers and radiologic techniques.

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    Cite

    APA: Copy

    EBRAHIMI, HEDYEH, NADERIAN, MOHAMMADREZA, & SOHRABPOUR, AMIR ALI. (2016). NEW CONCEPTS ON PATHOGENESIS AND DIAGNOSIS OF LIVER FIBROSIS, A REVIEW ARTICLE. MIDDLE EAST JOURNAL OF DIGESTIVE DISEASES (MEJDD), 8(3), 166-178. SID. https://sid.ir/paper/319133/en

    Vancouver: Copy

    EBRAHIMI HEDYEH, NADERIAN MOHAMMADREZA, SOHRABPOUR AMIR ALI. NEW CONCEPTS ON PATHOGENESIS AND DIAGNOSIS OF LIVER FIBROSIS, A REVIEW ARTICLE. MIDDLE EAST JOURNAL OF DIGESTIVE DISEASES (MEJDD)[Internet]. 2016;8(3):166-178. Available from: https://sid.ir/paper/319133/en

    IEEE: Copy

    HEDYEH EBRAHIMI, MOHAMMADREZA NADERIAN, and AMIR ALI SOHRABPOUR, “NEW CONCEPTS ON PATHOGENESIS AND DIAGNOSIS OF LIVER FIBROSIS, A REVIEW ARTICLE,” MIDDLE EAST JOURNAL OF DIGESTIVE DISEASES (MEJDD), vol. 8, no. 3, pp. 166–178, 2016, [Online]. Available: https://sid.ir/paper/319133/en

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