ASSOCIATION OF SMOKING WITH SEMEN QUALITY AND μ-CALPAIN LEVEL IN NORMOSPERMIA: A CASE-CONTROL STUDY

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ASHTARY LARKY DAMOON; GHAFFARI MOHAMMAD ALI; NOORBEHBAHANI MOZHGAN; ALIPOUR MEYSAM

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Journal Paper

Paper Information

Journal: JOURNAL OF FAMILY AND REPRODUCTIVE HEALTH Year:2016 | Volume:10 | Issue:1 Page(s): 15-20

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Title

ASSOCIATION OF SMOKING WITH SEMEN QUALITY AND μ-CALPAIN LEVEL IN NORMOSPERMIA: A CASE-CONTROL STUDY

Author(s)

ASHTARY LARKY DAMOON | GHAFFARI MOHAMMAD ALI | NOORBEHBAHANI MOZHGAN | ALIPOUR MEYSAM | Issue Writer Certificate

Keywords

CASE-CONTROL STUDY

SMOKING

SEMEN

CALPAIN

Abstract

Objective: CALPAINs are a family of Ca2+ dependent proteases. There is some evidence that CALPAINs involved in fusion process that occurs between spermatozoa and the oocyte. The current study aimed to investigate the association of SMOKING with SEMEN quality and μ-calpain level.Materials and methods: This CASE-CONTROL STUDY was conducted on 117 normospermia males between June 2013 and march 2014 in Jahad Laboratory in ahvaz, Iran. The SEMEN samples were collected from male smokers (n=50) and non-smokers (n=67). We divided these participants as light, moderate, or heavy smokers based on their cigarettes per day (CPD). ELISA assays were used to measure μ-calpain concentration. All SEMEN samples were analyzed according to World Health Organization guidelines.Results: The analysis of SEMEN showed the volume, concentration, motility and morphology of SEMEN were significantly lower among the smoker men than the non-smoker men. Also this significant difference was observed based on the number (light, moderate and heavy smokers) and duration (short term and long term smoker) of SMOKING. Although, showed no significant difference between m-calpain of smoker men and non-smoker men. CPD showed negatively correlation with SEMEN volume, concentration, motility and morphology of sperm.Conclusion: Sperm quality was negatively correlated with CPD and duration of SMOKING. However, there is no significant correlation between SMOKING and μ-calpain concentration.

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APA: Copy

ASHTARY LARKY, DAMOON, GHAFFARI, MOHAMMAD ALI, NOORBEHBAHANI, MOZHGAN, & ALIPOUR, MEYSAM. (2016). ASSOCIATION OF SMOKING WITH SEMEN QUALITY AND μ-CALPAIN LEVEL IN NORMOSPERMIA: A CASE-CONTROL STUDY. JOURNAL OF FAMILY AND REPRODUCTIVE HEALTH, 10(1), 15-20. SID. https://sid.ir/paper/320927/en

Vancouver: Copy

ASHTARY LARKY DAMOON, GHAFFARI MOHAMMAD ALI, NOORBEHBAHANI MOZHGAN, ALIPOUR MEYSAM. ASSOCIATION OF SMOKING WITH SEMEN QUALITY AND μ-CALPAIN LEVEL IN NORMOSPERMIA: A CASE-CONTROL STUDY. JOURNAL OF FAMILY AND REPRODUCTIVE HEALTH[Internet]. 2016;10(1):15-20. Available from: https://sid.ir/paper/320927/en

IEEE: Copy

DAMOON ASHTARY LARKY, MOHAMMAD ALI GHAFFARI, MOZHGAN NOORBEHBAHANI, and MEYSAM ALIPOUR, “ASSOCIATION OF SMOKING WITH SEMEN QUALITY AND μ-CALPAIN LEVEL IN NORMOSPERMIA: A CASE-CONTROL STUDY,” JOURNAL OF FAMILY AND REPRODUCTIVE HEALTH, vol. 10, no. 1, pp. 15–20, 2016, [Online]. Available: https://sid.ir/paper/320927/en

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