Demographic changes of hepatitis B virus infection in Iran for the last two decades

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Mohaghegh Shelmani Hamid; KARAYIANNIS PETER; ASHTARI SARA; Mahmanzar Mohammad Amin; Khanabadi Binazir; Modami Niusha; GHOLIPOUR FATEMEH; ZARE FATEMEH; ZALI MOHAMMAD REZA

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Journal: Gastroenterology and Hepatology From Bed to Bench Year:2017 | Volume:10 | Issue:Suppl 1 Page(s): 38-43

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Title

Demographic changes of hepatitis B virus infection in Iran for the last two decades

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Keywords

Hepatitis B virus

hepatitis B surface antigen (HBsAg)

Epidemiology

Vaccination

Iran

Abstract

Aim: The objective of this study was to evaluate the impact of the Hepatitis B virus (HBV) Vaccination program, 24 years after its implementation, by analyzing patients with hepatitis B surface antigen (HBsAg) infection based on gender and age group. Background: Since the launch of the first universal Vaccination program against HBV in Iran in 1993, the epidemiological pattern of HBV prevalence may have changed in our country. Methods: All data for this cross-sectional study were collected from medical records of HBsAg positive patients, who were referred to the Golhak and Armin private laboratories and also to the Gastrointestinal Department of Tehran’ s Taleghani Hospital and Day Hospital in Iran over a period of 5 years (2011-2016). In total, 8, 606 HBsAg positive subjects were assessed according to gender and age group. Results: The rates of HBsAg carriage were 0. 8%, 7. 8%, 49. 3%, 27. 9% and 14. 1% among subjects under 14 years old, 15-24 years, 25-44 years, 45-59 years and those older than 60 years, respectively. According to the age subgroup analyses; the highest (26. 2%) and lowest (0. 6%) rate of HBsAg positivity was seen in the 31-40 age group and younger than 10 year old children, respectively. Conclusion: Global Vaccination against hepatitis B has significantly reduced carrier rates among children and teenagers under 20 years old in this country. Nevertheless, HBsAg carriers still remain highly prevalent among 25-35-year age group. Therefore, the decline is limited to the younger population born after 1993, and it remains high in the middle-aged individuals.

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APA: Copy

Mohaghegh Shelmani, Hamid, KARAYIANNIS, PETER, ASHTARI, SARA, Mahmanzar, Mohammad Amin, Khanabadi, Binazir, Modami, Niusha, GHOLIPOUR, FATEMEH, ZARE, FATEMEH, & ZALI, MOHAMMAD REZA. (2017). Demographic changes of hepatitis B virus infection in Iran for the last two decades. GASTROENTEROLOGY AND HEPATOLOGY FROM BED TO BENCH, 10(Suppl 1), 38-43. SID. https://sid.ir/paper/324894/en

Vancouver: Copy

Mohaghegh Shelmani Hamid, KARAYIANNIS PETER, ASHTARI SARA, Mahmanzar Mohammad Amin, Khanabadi Binazir, Modami Niusha, GHOLIPOUR FATEMEH, ZARE FATEMEH, ZALI MOHAMMAD REZA. Demographic changes of hepatitis B virus infection in Iran for the last two decades. GASTROENTEROLOGY AND HEPATOLOGY FROM BED TO BENCH[Internet]. 2017;10(Suppl 1):38-43. Available from: https://sid.ir/paper/324894/en

IEEE: Copy

Hamid Mohaghegh Shelmani, PETER KARAYIANNIS, SARA ASHTARI, Mohammad Amin Mahmanzar, Binazir Khanabadi, Niusha Modami, FATEMEH GHOLIPOUR, FATEMEH ZARE, and MOHAMMAD REZA ZALI, “Demographic changes of hepatitis B virus infection in Iran for the last two decades,” GASTROENTEROLOGY AND HEPATOLOGY FROM BED TO BENCH, vol. 10, no. Suppl 1, pp. 38–43, 2017, [Online]. Available: https://sid.ir/paper/324894/en

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