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Information Journal Paper

Title

THE PREVENTIVE ROLE OF LOW-DOSE INTRAVENOUS KETAMINE ON POSTOPERATIVE SHIVERING IN CHILDREN: A PLACEBO RANDOMIZED CONTROLLED TRIAL

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Abstract

 Background: Postoperative SHIVERING is a major problem in CHILDREN undergoing general anesthesia.Objectives: The aim of the present study was to investigate the role of low-dose intravenous KETAMINE for prevention of SHIVERING after induction of general anesthesia in CHILDREN who had undergone tonsillectomy.Patient sand Methods: This was a randomized, double-blinded, placebo-controlled trial including 80 CHILDREN, of American society of anesthesiologists (ASA) physical status I or II, scheduled for tonsillectomy under general anesthesia who were randomly assigned to an intravenous KETAMINE (0.5 mg/kg, n=40; group K) group or matched dose placebo (n=40; group N) group. Surgical and demographic data, unexpected side effects, and the occurrence of SHIVERING for each child were assessed by a blinded observer at the following time points: T0, in the recovery room; T10, at 10 minutes; T20, at 20 minutes; T30, and at 30 minutes.Results: With regards to the demographic and surgical data, no significant differences between the two study groups were observed (P³ 0.05). SHIVERING intensity in CHILDREN who had received KETAMINE was significantly lower than CHILDREN who had not received KETAMINE, at T0, T10, T20, and T30 after arrival (P<0.05). There were no significant differences in hallucination, nausea, vomiting, hemodynamic dysfunction, blurred vision, and seizure in the K group compared with the N group (P³ 0.05).Conclusions: Administration of intravenous KETAMINE at a dosage of 0.5 mg/kg immediately after anesthesia induction had a preventive effect on SHIVERING intensity without hemodynamic alterations in CHILDREN undergoing general anesthesia for tonsillectomy.

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    APA: Copy

    SANIE, MOHAMMAD SADEGH, KALANI, NAVID, GHOBADIFAR, MOHAMED AMIN, ZABETIAN, HASSAN, & HOSSEINI, MEHDI. (2016). THE PREVENTIVE ROLE OF LOW-DOSE INTRAVENOUS KETAMINE ON POSTOPERATIVE SHIVERING IN CHILDREN: A PLACEBO RANDOMIZED CONTROLLED TRIAL. ANESTHESIOLOGY AND PAIN MEDICINE, 6(3), 0-0. SID. https://sid.ir/paper/328596/en

    Vancouver: Copy

    SANIE MOHAMMAD SADEGH, KALANI NAVID, GHOBADIFAR MOHAMED AMIN, ZABETIAN HASSAN, HOSSEINI MEHDI. THE PREVENTIVE ROLE OF LOW-DOSE INTRAVENOUS KETAMINE ON POSTOPERATIVE SHIVERING IN CHILDREN: A PLACEBO RANDOMIZED CONTROLLED TRIAL. ANESTHESIOLOGY AND PAIN MEDICINE[Internet]. 2016;6(3):0-0. Available from: https://sid.ir/paper/328596/en

    IEEE: Copy

    MOHAMMAD SADEGH SANIE, NAVID KALANI, MOHAMED AMIN GHOBADIFAR, HASSAN ZABETIAN, and MEHDI HOSSEINI, “THE PREVENTIVE ROLE OF LOW-DOSE INTRAVENOUS KETAMINE ON POSTOPERATIVE SHIVERING IN CHILDREN: A PLACEBO RANDOMIZED CONTROLLED TRIAL,” ANESTHESIOLOGY AND PAIN MEDICINE, vol. 6, no. 3, pp. 0–0, 2016, [Online]. Available: https://sid.ir/paper/328596/en

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