EFFECTS OF MYCELIUM EXTRACT, CONDIDIA AND CATALASE ENZYME OF ASPERGILLUS FUMIGATUS ON THE NITRIC OXIDE PRODUCTION OF MACROPHAGES AND NEUTROPHILS IN MURINE MODEL

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

ROUDBAR MOHAMMADI SH.; ZAVARAN HOSSEINI A.; KHOSRAVI ALI REZA; YADGARI M.H.; SHOKOUH AMIRI M.R.; GHAFFARIFAR FATEMEH

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: KOWSAR MEDICAL JOURNAL Year:2008 | Volume:12 | Issue:4 Page(s): 299-304

Download Full-Text

Persian Verion

View:

1,283

Download:

Cites:

Information Journal Paper

Title

EFFECTS OF MYCELIUM EXTRACT, CONDIDIA AND CATALASE ENZYME OF ASPERGILLUS FUMIGATUS ON THE NITRIC OXIDE PRODUCTION OF MACROPHAGES AND NEUTROPHILS IN MURINE MODEL

Author(s)

Keywords

ASPERGILLUS FUMIGATUSQ3

NITRIC OXIDEQ3

IMMUNE SYSTEMQ3

Abstract

Background & Aim: Invasive aspergillosis is one of the lethal and important diseases in immunocompromise, diabetic, bone marrow recipient and aids hosts. NITRIC OXIDE is one of the anti microbial anti inflammation products that in non special defense is important , this research performed to evaluate the effect of mycelium extract, conidia and catalase enzyme of ASPERGILLUS FUMIGATUS an the production of NITRIC OXIDE from macrophages and neutrophills in murin model.Material & Method: Catalase enzyme was purified using Ione exchange chromatography technique. Then forty Balb/c mice were divided in to four groups and sensitized intraperitonealy by 300 mg of catalase, mycelium extract, adjuvant and with 1 × 106 conidia, respectively. Then all the mice were authorized under aseptic conditions. The neutrophils and macrophages of each group were separately exposed to catalase inducer and then the amount of NITRIC OXIDE production by each group was measured by qriess method.Results and Conclusion: production of NITRIC OXIDE in group the sensitized with catalase inducet had averagely more NITRIC OXIDE concentration comparing to the other groups (P £ 0.05). Thus catalase enzyme inducer increased. The production of NITRIC OXIDE in the peritoneal macrophages and neutrophils, which consequently increased their killing potential against ASPERGILLUS FUMIGATUS infections. Whereas conidia and mycellium extract did not showe such as effect.It is conculuded that catalase maybe used for induction of IMMUNE SYSTEM and to design a vaccine model.

Cites

No record.

References

No record.

Cite

APA: Copy

ROUDBAR MOHAMMADI, SH., ZAVARAN HOSSEINI, A., KHOSRAVI, ALI REZA, YADGARI, M.H., SHOKOUH AMIRI, M.R., & GHAFFARIFAR, FATEMEH. (2008). EFFECTS OF MYCELIUM EXTRACT, CONDIDIA AND CATALASE ENZYME OF ASPERGILLUS FUMIGATUS ON THE NITRIC OXIDE PRODUCTION OF MACROPHAGES AND NEUTROPHILS IN MURINE MODEL. KOWSAR MEDICAL JOURNAL, 12(4), 299-304. SID. https://sid.ir/paper/33021/en

Vancouver: Copy

ROUDBAR MOHAMMADI SH., ZAVARAN HOSSEINI A., KHOSRAVI ALI REZA, YADGARI M.H., SHOKOUH AMIRI M.R., GHAFFARIFAR FATEMEH. EFFECTS OF MYCELIUM EXTRACT, CONDIDIA AND CATALASE ENZYME OF ASPERGILLUS FUMIGATUS ON THE NITRIC OXIDE PRODUCTION OF MACROPHAGES AND NEUTROPHILS IN MURINE MODEL. KOWSAR MEDICAL JOURNAL[Internet]. 2008;12(4):299-304. Available from: https://sid.ir/paper/33021/en

IEEE: Copy

SH. ROUDBAR MOHAMMADI, A. ZAVARAN HOSSEINI, ALI REZA KHOSRAVI, M.H. YADGARI, M.R. SHOKOUH AMIRI, and FATEMEH GHAFFARIFAR, “EFFECTS OF MYCELIUM EXTRACT, CONDIDIA AND CATALASE ENZYME OF ASPERGILLUS FUMIGATUS ON THE NITRIC OXIDE PRODUCTION OF MACROPHAGES AND NEUTROPHILS IN MURINE MODEL,” KOWSAR MEDICAL JOURNAL, vol. 12, no. 4, pp. 299–304, 2008, [Online]. Available: https://sid.ir/paper/33021/en

Related Journal Papers