ALOE VERA AQUEOUS EXTRACT EFFECT ON MORPHINE WITHDRAWAL SYNDROME IN MORPHINE-DEPENDENT FEMALE RATS

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SHAHRAKI MOHAMMAD REZA; MIRSHEKARI HAMIDEH; SABRI AZAME

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Paper Information

Journal: International Journal of High Risk Behaviors and Addiction Year:2014 | Volume:3 | Issue:3 Page(s): 0-0

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Title

ALOE VERA AQUEOUS EXTRACT EFFECT ON MORPHINE WITHDRAWAL SYNDROME IN MORPHINE-DEPENDENT FEMALE RATS

Author(s)

SHAHRAKI MOHAMMAD REZA | MIRSHEKARI HAMIDEH | SABRI AZAME | Issue Writer Certificate

Keywords

MORPHINE

SUBSTANCE WITHDRAWAL SYNDROME

ALOE VERA

RATS

Abstract

Background: ALOE VERA is a medicinal herb used as an anti-inflammatory and sedative agent.Objectives: The current study aimed to evaluate the effect of ALOE VERA aqueous extract on MORPHINE withdrawal symptoms in MORPHINE-dependent female RATS.Patients and Methods: The current research was performed on 40 female Wista-Albino RATS which were made dependent on MORPHINE using Houshyar protocol and were randomly divided into five groups (A, B, C, D, and E). Group A did not receive any agent in the period of handling but other groups (B, C, D and E) received 5, 10, 20 and 40 mg/kg of ALOE VERA aqueous extract by gavage, three times daily for a week, respectively. Withdrawal symptoms, stool form, agitation, disparity, floppy eyelids, and body mass variations were checked for 10 days. The obtained data were analyzed using SPSS v.11 software, and Friedman, Kruskal-Wallis, and Mann-Whitney statistical tests. Statistical difference was considered significant (P<0.05).Results: The results of the present study showed that agitation, disparity, and floppy eyelids in group E were significantly higher than those of others groups, however, these symptoms in group C were significantly lower than those of the other groups.Conclusions: The results of the present study revealed that the ALOE VERA aqueous extract had various effects on MORPHINE withdrawal syndrome in MORPHINE-dependent female RATS.

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APA: Copy

SHAHRAKI, MOHAMMAD REZA, MIRSHEKARI, HAMIDEH, & SABRI, AZAME. (2014). ALOE VERA AQUEOUS EXTRACT EFFECT ON MORPHINE WITHDRAWAL SYNDROME IN MORPHINE-DEPENDENT FEMALE RATS. INTERNATIONAL JOURNAL OF HIGH RISK BEHAVIORS AND ADDICTION, 3(3), 0-0. SID. https://sid.ir/paper/330925/en

Vancouver: Copy

SHAHRAKI MOHAMMAD REZA, MIRSHEKARI HAMIDEH, SABRI AZAME. ALOE VERA AQUEOUS EXTRACT EFFECT ON MORPHINE WITHDRAWAL SYNDROME IN MORPHINE-DEPENDENT FEMALE RATS. INTERNATIONAL JOURNAL OF HIGH RISK BEHAVIORS AND ADDICTION[Internet]. 2014;3(3):0-0. Available from: https://sid.ir/paper/330925/en

IEEE: Copy

MOHAMMAD REZA SHAHRAKI, HAMIDEH MIRSHEKARI, and AZAME SABRI, “ALOE VERA AQUEOUS EXTRACT EFFECT ON MORPHINE WITHDRAWAL SYNDROME IN MORPHINE-DEPENDENT FEMALE RATS,” INTERNATIONAL JOURNAL OF HIGH RISK BEHAVIORS AND ADDICTION, vol. 3, no. 3, pp. 0–0, 2014, [Online]. Available: https://sid.ir/paper/330925/en

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