مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

1,025
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

1,077
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

4

Information Journal Paper

Title

DENDROSOMAL NANO-CURCUMIN, THE NOVEL FORMULATION TO IMPROVE THE ANTICANCER PROPERTIES OF CURCUMIN

Pages

  143-158

Abstract

 Curcumin is a hydrophobic polyphenol extracted from the plant curcuma longa with established antiCANCER properties. However, CURCUMIN benefits have been impaired by its very low water solubility, low absorption, rapid metabolism and clearance from the body. Recently, NANOTECHNOLOGY promises to be helpful in development of drugs delivery systems by recent advances in macromolecular design of nanocarriers. In this review, we present the novel generation of nano-vehicles termed DENDROSOMEs which are readily synthesized from esterification of oleic acid and polyethylene glycol residues. DENDROSOMEs efficiently encapsulate CURCUMIN in a spherical micellar or polymersome structures which leads to increase aqueous solubility of this hydrophobic agent and higher bioavailability of CURCUMIN. AntiCANCER potency of this nanoformulation was confirmed in different mouse and human CANCER cells including fibrosarcoma, colon, glioblastoma, bladder, gastric, breast and hepatocellular carcinoma in vitro and vivo. It has also demonstrated that this nano preparation has no cytotoxicity effects on normal cells. Finally, these results introduce dendrosomal CURCUMIN as potent anti-tumor agent although further clinical examinations are needed.

Cites

References

  • No record.

    • Cite

    APA: Copy

    TAHMASEBI BIRGANI, MARYAM, ERFANI MOGHADAM, VAHID, BABAEI, ESMAIL, NAJAFI, FARHAD, ZAMANI, MINA, SHARIATI, MOLOOD, NAZEM, SHIMA, FARHANGI, BAHARAK, MOTAHARI, PARIA, & SADEGHIZADEH, MAJID. (2015). DENDROSOMAL NANO-CURCUMIN, THE NOVEL FORMULATION TO IMPROVE THE ANTICANCER PROPERTIES OF CURCUMIN. PROGRESS IN BIOLOGICAL SCIENCES, 5(2), 143-158. SID. https://sid.ir/paper/331235/en

    Vancouver: Copy

    TAHMASEBI BIRGANI MARYAM, ERFANI MOGHADAM VAHID, BABAEI ESMAIL, NAJAFI FARHAD, ZAMANI MINA, SHARIATI MOLOOD, NAZEM SHIMA, FARHANGI BAHARAK, MOTAHARI PARIA, SADEGHIZADEH MAJID. DENDROSOMAL NANO-CURCUMIN, THE NOVEL FORMULATION TO IMPROVE THE ANTICANCER PROPERTIES OF CURCUMIN. PROGRESS IN BIOLOGICAL SCIENCES[Internet]. 2015;5(2):143-158. Available from: https://sid.ir/paper/331235/en

    IEEE: Copy

    MARYAM TAHMASEBI BIRGANI, VAHID ERFANI MOGHADAM, ESMAIL BABAEI, FARHAD NAJAFI, MINA ZAMANI, MOLOOD SHARIATI, SHIMA NAZEM, BAHARAK FARHANGI, PARIA MOTAHARI, and MAJID SADEGHIZADEH, “DENDROSOMAL NANO-CURCUMIN, THE NOVEL FORMULATION TO IMPROVE THE ANTICANCER PROPERTIES OF CURCUMIN,” PROGRESS IN BIOLOGICAL SCIENCES, vol. 5, no. 2, pp. 143–158, 2015, [Online]. Available: https://sid.ir/paper/331235/en

    Related Journal Papers

  • No record.

    • Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops






    Move to top
    telegram sharing button
    whatsapp sharing button
    linkedin sharing button
    twitter sharing button
    email sharing button
    email sharing button
    email sharing button
    sharethis sharing button