THE ROLE OF PROBIOTICS IN CANCER TREATMENT: EMPHASIS ON THEIR IN VIVO AND IN VITRO ANTI-METASTATIC EFFECTS

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MOTEVASELI ELAHE; DIANATPOUR ALI; GHAFOURI FARD SOUDEH

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Journal Paper

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Journal: International Journal of Molecular and Cellular Medicine Year:2017 | Volume:6 | Issue:2 Page(s): 66-76

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Title

THE ROLE OF PROBIOTICS IN CANCER TREATMENT: EMPHASIS ON THEIR IN VIVO AND IN VITRO ANTI-METASTATIC EFFECTS

Author(s)

MOTEVASELI ELAHE | DIANATPOUR ALI | GHAFOURI FARD SOUDEH | Issue Writer Certificate

Keywords

PROBIOTICS

LACTOBACILLI

CANCER

METASTASIS

INVASION

Abstract

PROBIOTICS are defined as live bacteria and yeasts that exert beneficial effects for health. Among their various effects, anti-cancer properties have been highlighted in recent years. Such effects include suppression of the growth of microbiota implicated in the production of mutagens and carcinogens, alteration in carcinogen metabolism and protection of DNA from oxidative damage as well as regulation of immune system. We performed a computerized search of the MEDLINE/PUBMED databases with key word CANCER, PROBIOTICS, LACTOBACILLI, METASTASIS and INVASION. Cell line studies as well as animal models and human studies have shown the therapeutic effects of PROBIOTICS in reduction of INVASION and METASTASIS in CANCER cells. These results support the beneficial effects of PROBIOTICS bothin vitro and in vivo. However, pre-clinical or clinical studies are not enough to decide about their application.

Cites

Anti-Proliferative Effects of Two New Lactobacillus Strains of Human Origin on Caco-2 Cell Line

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APA: Copy

MOTEVASELI, ELAHE, DIANATPOUR, ALI, & GHAFOURI FARD, SOUDEH. (2017). THE ROLE OF PROBIOTICS IN CANCER TREATMENT: EMPHASIS ON THEIR IN VIVO AND IN VITRO ANTI-METASTATIC EFFECTS. INTERNATIONAL JOURNAL OF MOLECULAR AND CELLULAR MEDICINE, 6(2), 66-76. SID. https://sid.ir/paper/332188/en

Vancouver: Copy

MOTEVASELI ELAHE, DIANATPOUR ALI, GHAFOURI FARD SOUDEH. THE ROLE OF PROBIOTICS IN CANCER TREATMENT: EMPHASIS ON THEIR IN VIVO AND IN VITRO ANTI-METASTATIC EFFECTS. INTERNATIONAL JOURNAL OF MOLECULAR AND CELLULAR MEDICINE[Internet]. 2017;6(2):66-76. Available from: https://sid.ir/paper/332188/en

IEEE: Copy

ELAHE MOTEVASELI, ALI DIANATPOUR, and SOUDEH GHAFOURI FARD, “THE ROLE OF PROBIOTICS IN CANCER TREATMENT: EMPHASIS ON THEIR IN VIVO AND IN VITRO ANTI-METASTATIC EFFECTS,” INTERNATIONAL JOURNAL OF MOLECULAR AND CELLULAR MEDICINE, vol. 6, no. 2, pp. 66–76, 2017, [Online]. Available: https://sid.ir/paper/332188/en

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