TREATMENT OF CANDIDA VAGINITIS: COMPARISON OF SINGLE AND SEQUENTIAL DOSE OF FLUCONAZOLE

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KAMALI F.; GHARIBI TAYEBEH; NAEIMI B.; AFSHARI P.

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Paper Information

Journal: IRANIAN SOUTH MEDICAL JOURNAL (ISMJ) Year:2003 | Volume:6 | Issue:1 Page(s): 25-30

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Information Journal Paper

Title

TREATMENT OF CANDIDA VAGINITIS: COMPARISON OF SINGLE AND SEQUENTIAL DOSE OF FLUCONAZOLE

Author(s)

KAMALI F. | GHARIBI TAYEBEH | NAEIMI B. | AFSHARI P. | Issue Writer Certificate

Keywords

FLUCONAZOLEQ3

VAGINITISQ3

CANDIDIASISQ2

FUNGALQ3

Abstract

FLUCONAZOLE is one of the triazole antifungal agents for Candida albican. For comparison of single versus sequential dose of FLUCONAZOLE, a double-blind randomized clinical trial was counducted on 80 married 20-45 years old women who had chronic vaginal CANDIDIASIS. The patients randomized into two groups, 40 patients received two ( zero and 72 hours) doses of FLUCONAZOLE and the other group received one 150mg dose of the drug at zero and placebo at 72 hours later. The patients were examined at 2 & 6 weeks after treatment. The groups showed decreased signs and symptoms of vaginal CANDIDIASIS during examination periods, however there was no significant difference between groups (p>0.05). Wet mount & culture were negative in the 2nd week in two groups but at the 6th week after treatment, 95.3% and 72.5% of patients in control and case groups, respectively had negative results (p<0.05). Therefore, single and sequential doses of FLUCONAZOLE have the same result for treatment of vaginal CANDIDIASIS but sequential dose reduces the relapse rate of the disease.

Cites

COMPARISON OF COMBINED USE OF FLUCONAZOLE AND CLOTRIMAZOLE WITH THE SEQUENTIAL DOSE OF FLUCONAZOLE IN THE TREATMENT OF RECURRENT CANDIDA VAGINITIS

References

شیوع کاندیدیازیس سرویکوواژینال در زنان مراجعه کننده به مراکز بهداشتی درمانی شهرستان شهرکرد

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APA: Copy

KAMALI, F., GHARIBI, TAYEBEH, NAEIMI, B., & AFSHARI, P.. (2003). TREATMENT OF CANDIDA VAGINITIS: COMPARISON OF SINGLE AND SEQUENTIAL DOSE OF FLUCONAZOLE. IRANIAN SOUTH MEDICAL JOURNAL (ISMJ), 6(1), 25-30. SID. https://sid.ir/paper/33736/en

Vancouver: Copy

KAMALI F., GHARIBI TAYEBEH, NAEIMI B., AFSHARI P.. TREATMENT OF CANDIDA VAGINITIS: COMPARISON OF SINGLE AND SEQUENTIAL DOSE OF FLUCONAZOLE. IRANIAN SOUTH MEDICAL JOURNAL (ISMJ)[Internet]. 2003;6(1):25-30. Available from: https://sid.ir/paper/33736/en

IEEE: Copy

F. KAMALI, TAYEBEH GHARIBI, B. NAEIMI, and P. AFSHARI, “TREATMENT OF CANDIDA VAGINITIS: COMPARISON OF SINGLE AND SEQUENTIAL DOSE OF FLUCONAZOLE,” IRANIAN SOUTH MEDICAL JOURNAL (ISMJ), vol. 6, no. 1, pp. 25–30, 2003, [Online]. Available: https://sid.ir/paper/33736/en

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