EFFECT OF CINNAMON ON LIPID PROFILE, LIVER ENZYMES, INSULIN RESISTANCE AND HS -CRP INFLAMMATORY FACTOR, IN PATIENTS WITH NONALCOHOLIC FATTY LIVER DISEASE

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ASKARI F.; RASHIDKHANI B.; HEKMATDOOST A.

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Paper Information

Journal: NUTRITION AND FOOD SCIENCES RESEARCH Year:2014 | Volume:1 | Issue:SUPPL. (1) Page(s): 76-77

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Title

EFFECT OF CINNAMON ON LIPID PROFILE, LIVER ENZYMES, INSULIN RESISTANCE AND HS -CRP INFLAMMATORY FACTOR, IN PATIENTS WITH NONALCOHOLIC FATTY LIVER DISEASE

Author(s)

ASKARI F. | RASHIDKHANI B. | HEKMATDOOST A. | Issue Writer Certificate

Keywords

NAFLD

CINNAMON

INSULIN RESISTANCE

LIVER ENZYMES

LIPID PROFILE

HUMAN

Abstract

Backgrounds: Non-alcoholic fatty liver disease (NAFLD) is the most prevalent cause of hepatic injury in the world.Modulating the INSULIN RESISTANCE and oxidative stress is one of the most important therapeutic strategies for this disease. This study aimed to investigate the hypothesis that supplementation with CINNAMON, exerts an insulin sensitizer effect in patients with NAFLD.Methods: In a double-blind, placebo-controlled trial with 2 parallel groups, 50 patients with NAFLD, were randomized to receive daily supplementation with either 2 capsules of CINNAMON (each capsule contain 750 mg CINNAMON) or 2 placebo capsules daily for 12 weeks. Both groups were advised a balanced diet and physical activity during the intervention. Results: A significant decrease in HOMA (Homeostatic Model Assessment) index, FBS (fasting blood glucose), total cholesterol, triglyceride, ALT (alanine aminotransferase), AST (aspartate aminotransferase), GGT (gamma glutamine transpeptidase), and hs-CRP parameters were seen in treatment group (p<0.05), whereas there was no significant change in serum HDL level (p = 0.103). In both groups LDL decreased significantly (p<0.05).Conclusion: the study suggests that taking 1500mg CINNAMON daily may be effective in improving NAFLD characteristics.

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APA: Copy

ASKARI, F., RASHIDKHANI, B., & HEKMATDOOST, A.. (2014). EFFECT OF CINNAMON ON LIPID PROFILE, LIVER ENZYMES, INSULIN RESISTANCE AND HS -CRP INFLAMMATORY FACTOR, IN PATIENTS WITH NONALCOHOLIC FATTY LIVER DISEASE. NUTRITION AND FOOD SCIENCES RESEARCH, 1(SUPPL. (1)), 76-77. SID. https://sid.ir/paper/342658/en

Vancouver: Copy

ASKARI F., RASHIDKHANI B., HEKMATDOOST A.. EFFECT OF CINNAMON ON LIPID PROFILE, LIVER ENZYMES, INSULIN RESISTANCE AND HS -CRP INFLAMMATORY FACTOR, IN PATIENTS WITH NONALCOHOLIC FATTY LIVER DISEASE. NUTRITION AND FOOD SCIENCES RESEARCH[Internet]. 2014;1(SUPPL. (1)):76-77. Available from: https://sid.ir/paper/342658/en

IEEE: Copy

F. ASKARI, B. RASHIDKHANI, and A. HEKMATDOOST, “EFFECT OF CINNAMON ON LIPID PROFILE, LIVER ENZYMES, INSULIN RESISTANCE AND HS -CRP INFLAMMATORY FACTOR, IN PATIENTS WITH NONALCOHOLIC FATTY LIVER DISEASE,” NUTRITION AND FOOD SCIENCES RESEARCH, vol. 1, no. SUPPL. (1), pp. 76–77, 2014, [Online]. Available: https://sid.ir/paper/342658/en

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