Protective Effects of Vitamin E and Selenium on Liver Tissue Damages Induced by Electromagnetic Field: An Ultrastructural Study

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Kiafar Effat; Tayefi Nasrabadi Hamid; ABEDELAHI ALI; SHOOREI HAMED; Majdi Seghinsara Abbas

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Crescent Journal of Medical and Biological Sciences Year:2018 | Volume:5 | Issue:4 Page(s): 338-344

Download Full-Text

View:

172

Download:

157

Cites:

Information Journal Paper

Title

Protective Effects of Vitamin E and Selenium on Liver Tissue Damages Induced by Electromagnetic Field: An Ultrastructural Study

Author(s)

Keywords

Electromagnetic field

Oxidative stress

Vitamin E

Selenium

Liver

Abstract

Objectives: The aim of this study was to investigate the effects of Vitamin E and Selenium (Se) on some Liver enzymes, some Oxidative stress markers, and the Liver structure of mice using light and transmission electron microscope (TEM) following long-term Electromagnetic field (EMF) exposure. Materials and Methods: Forty-eight female Balb/c mice were randomly divided into 6 groups (n = 8) as follows: control, EMF, EMF plus Vitamin E, EMF plus Se, EMF plus Vitamin E and Se, and Vitamin E and Se groups. Mice in EMF group were exposed to EMF (3 mT and 50 Hz), 4 hours a day for 2 months. Treated mice received 0. 1 mg/kg Se and/or 1. 35 mg/kg Vitamin E for 2 months intraperitoneally and daily. Anesthesia in mice were induced by ketamine/xylazine (10/2 mg/kg) and after taking blood samples for investigating some Liver enzymes, mice were killed by cervical dislocation and their Liver were removed by light and TEM for morphological studies and also evaluating some Oxidative stress factors. Results: The level of malondialdehyde (MDA) increased in the Liver of mice under EMF while the levels of superoxide dismutase (SOD), glutathione peroxidase (GPx), and total antioxidant capacity (TAC) decreased (P < 0. 05). Treated EMF groups by Vitamin E plus Se and Vitamin E alone significantly improved the levels of SOD, GPx, and TAC (P < 0. 05) while treatment with Se did not result in a significant effect. Histopathological analysis revealed that the Livers of the mice’ that received Vitamin E plus Se and Vitamin E had fewer morphological changes compared to those of EMF groups. Moreover, some Liver enzymes such as serum aminotransferase (AST), serum alanine aminotransferase (ALT), and alkaline phosphatase (ALP) significantly increased in the EMF group in comparison with those of other groups except for the EMF group treated with Se. Conclusions: The results of the study indicated that although Se had no significant effects per se, Vitamin E and Vitamin E + Se significantly reduced Oxidative stress and some Liver enzymes.

Cites

Effect of Vitamin E and Sodium Selenite on the Expression of Bax and Bcl2 Genes and Renal Histopathology in the Electromagnetic Field-Exposed Mice

References

Cite

APA: Copy

Kiafar, Effat, Tayefi Nasrabadi, Hamid, ABEDELAHI, ALI, SHOOREI, HAMED, & Majdi Seghinsara, Abbas. (2018). Protective Effects of Vitamin E and Selenium on Liver Tissue Damages Induced by Electromagnetic Field: An Ultrastructural Study. CRESCENT JOURNAL OF MEDICAL AND BIOLOGICAL SCIENCES, 5(4), 338-344. SID. https://sid.ir/paper/344952/en

Vancouver: Copy

Kiafar Effat, Tayefi Nasrabadi Hamid, ABEDELAHI ALI, SHOOREI HAMED, Majdi Seghinsara Abbas. Protective Effects of Vitamin E and Selenium on Liver Tissue Damages Induced by Electromagnetic Field: An Ultrastructural Study. CRESCENT JOURNAL OF MEDICAL AND BIOLOGICAL SCIENCES[Internet]. 2018;5(4):338-344. Available from: https://sid.ir/paper/344952/en

IEEE: Copy

Effat Kiafar, Hamid Tayefi Nasrabadi, ALI ABEDELAHI, HAMED SHOOREI, and Abbas Majdi Seghinsara, “Protective Effects of Vitamin E and Selenium on Liver Tissue Damages Induced by Electromagnetic Field: An Ultrastructural Study,” CRESCENT JOURNAL OF MEDICAL AND BIOLOGICAL SCIENCES, vol. 5, no. 4, pp. 338–344, 2018, [Online]. Available: https://sid.ir/paper/344952/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops