OPTIMAL CONCENTRATIONS AND SYNERGISTIC EFFECTS OF SOME HERBAL EXTRACTS ON VIABILITY OF DERMAL FIBROBLASTS

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ZANDI MOHAMMAD; MASOUMIAN MAJID; SHARIATINIA ASGHAR; SANJABI MOHAMMAD REZA

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Journal Paper

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Journal: Gene, Cell and Tissue Year:2016 | Volume:3 | Issue:4 Page(s): 0-0

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Title

OPTIMAL CONCENTRATIONS AND SYNERGISTIC EFFECTS OF SOME HERBAL EXTRACTS ON VIABILITY OF DERMAL FIBROBLASTS

Author(s)

ZANDI MOHAMMAD | MASOUMIAN MAJID | SHARIATINIA ASGHAR | SANJABI MOHAMMAD REZA | Issue Writer Certificate

Keywords

HERBAL EXTRACTS

DERMAL FIBROBLASTS

VIABILITY

Abstract

Background: Many studies examine the antibacterial effects of medicinal plants; however, little research is done to evaluate their effects on different cell types, especially DERMAL FIBROBLASTS.Objectives: The current study aimed to study the effect of different concentrations of Aloe Vera, henna, chamomile, myrtle, mint, licorice, cinnamon, ginger and cedar extracts and their synergistic effects on the VIABILITY of DERMAL FIBROBLASTS.Methods: To evaluate the performance of HERBAL EXTRACTS on DERMAL FIBROBLASTS, in the first experiment different concentrations (6.25, 12.5, 25, 50, 100, 250, 500 and 1000g/mL) of the extracts were evaluated by the MTT cell proliferation assay. In the second experiment, the minimum effective concentrations of the plant extracts in triple combination were evaluated in the cells under study.Results: The minimum effective concentrations of henna, chamomile, myrtle, mint, cinnamon, ginger and cedar were 12.5, 6.25, 6.25, 6.25, 6.25, 12.5 and 12.5mg/mL, respectively. Results showed that, by comparing the minimum effective concentration of HERBAL EXTRACTS, the VIABILITY of DERMAL FIBROBLASTS significantly increased by cedar extract (P<0.05). Combination of Aloe Vera, licorice and mint extracts significantly increased the VIABILITY of DERMAL FIBROBLASTS (P<0.05).Conclusions: Based on the results of the current study, it was concluded that Aloe vera, licorice and mint extracts had synergistic effects on the VIABILITY of DERMAL FIBROBLASTS; in addition, the combination of Aloe vera and licorice with either henna or myrtle, and Aloe vera and mint with either cedar or ginger resulted in synergistic effects on VIABILITY of DERMAL FIBROBLASTS. The third category of triple combinations of HERBAL EXTRACTS with synergistic effects on the cells under study was the combination of Aloe Vera and mint with either chamomile or cinnamon and also Aloe vera and licorice with either myrtle or cedar.

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APA: Copy

ZANDI, MOHAMMAD, MASOUMIAN, MAJID, SHARIATINIA, ASGHAR, & SANJABI, MOHAMMAD REZA. (2016). OPTIMAL CONCENTRATIONS AND SYNERGISTIC EFFECTS OF SOME HERBAL EXTRACTS ON VIABILITY OF DERMAL FIBROBLASTS. GENE, CELL AND TISSUE, 3(4), 0-0. SID. https://sid.ir/paper/345180/en

Vancouver: Copy

ZANDI MOHAMMAD, MASOUMIAN MAJID, SHARIATINIA ASGHAR, SANJABI MOHAMMAD REZA. OPTIMAL CONCENTRATIONS AND SYNERGISTIC EFFECTS OF SOME HERBAL EXTRACTS ON VIABILITY OF DERMAL FIBROBLASTS. GENE, CELL AND TISSUE[Internet]. 2016;3(4):0-0. Available from: https://sid.ir/paper/345180/en

IEEE: Copy

MOHAMMAD ZANDI, MAJID MASOUMIAN, ASGHAR SHARIATINIA, and MOHAMMAD REZA SANJABI, “OPTIMAL CONCENTRATIONS AND SYNERGISTIC EFFECTS OF SOME HERBAL EXTRACTS ON VIABILITY OF DERMAL FIBROBLASTS,” GENE, CELL AND TISSUE, vol. 3, no. 4, pp. 0–0, 2016, [Online]. Available: https://sid.ir/paper/345180/en

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