IMMUNOHISTOCHEMICAL STUDY OF SEX HORMONAL RECEPTORS IN CANINE MAMMARY GLAND TUMORS

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SASANI F.; JAHANZAD ISA; GHOLAM HOSSEINI B.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Paper Information

Journal: Journal of Veterinary Research Year:2003 | Volume:58 | Issue:3 Page(s): 283-285

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Information Journal Paper

Title

IMMUNOHISTOCHEMICAL STUDY OF SEX HORMONAL RECEPTORS IN CANINE MAMMARY GLAND TUMORS

Author(s)

SASANI F. | JAHANZAD ISA | GHOLAM HOSSEINI B. | Issue Writer Certificate

Keywords

TUMORQ3

MAMMARY GLANDQ3

DOGQ2

IMMUNOHISTOCHEMISTRYQ2

SEX HORMONAL RECEPTORQ4

Abstract

Objective: In this research, immunohistochemical method was used to study estrogen and progesterone receptors in canine MAMMARY GLAND TUMORs.Animals: Six DOGs with MAMMARY GLAND TUMORs.Procedure: six out of 141 paraffin embedded blocks of canine MAMMARY GLAND TUMORs, were selected from files of veterinary pathology department, faculty of veterinary medicine, Tehran University. Tissue samples were processed then H&E and IMMUNOHISTOCHEMISTRY staining carried out on sections.Results: Neither of species showed positive reaction to oestrogenic receptor nor progestronic receptor.Conclusion: Reasons for negative reactions may be one of these situations: malignancy of TUMORs, destruction of antigens in processing of tissues. It is necessary to remind that human being TUMOR markers have been used on uterus of horse with positive reaction to these hormones. Carcinoma is often observed with mixed TUMORs. Because of malignancy of carcinomatous tissues, there were no positive reactions. In this study 1D5 monoclonal Ab for oestrogenic receptor and 1A6 colon for progesteronic receptor have been used.

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APA: Copy

SASANI, F., JAHANZAD, ISA, & GHOLAM HOSSEINI, B.. (2003). IMMUNOHISTOCHEMICAL STUDY OF SEX HORMONAL RECEPTORS IN CANINE MAMMARY GLAND TUMORS. JOURNAL OF VETERINARY RESEARCH, 58(3), 283-285. SID. https://sid.ir/paper/34689/en

Vancouver: Copy

SASANI F., JAHANZAD ISA, GHOLAM HOSSEINI B.. IMMUNOHISTOCHEMICAL STUDY OF SEX HORMONAL RECEPTORS IN CANINE MAMMARY GLAND TUMORS. JOURNAL OF VETERINARY RESEARCH[Internet]. 2003;58(3):283-285. Available from: https://sid.ir/paper/34689/en

IEEE: Copy

F. SASANI, ISA JAHANZAD, and B. GHOLAM HOSSEINI, “IMMUNOHISTOCHEMICAL STUDY OF SEX HORMONAL RECEPTORS IN CANINE MAMMARY GLAND TUMORS,” JOURNAL OF VETERINARY RESEARCH, vol. 58, no. 3, pp. 283–285, 2003, [Online]. Available: https://sid.ir/paper/34689/en

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