The effect of turmeric extract and sodium bentonite on some biochemical parameters in rats contaminated with Aflatoxin B1

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Rialy a.; SARIR H.; MOJTAHEDI M.; ABTAHI H.

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Journal: Journal of Veterinary Research Year:2017 | Volume:72 | Issue:3 Page(s): 355-363

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Title

The effect of turmeric extract and sodium bentonite on some biochemical parameters in rats contaminated with Aflatoxin B1

Author(s)

Rialy a. | SARIR H. | MOJTAHEDI M. | ABTAHI H. | Issue Writer Certificate

Keywords

aflatoxin B1Q1

turmeric extractQ2

sodium bentoniteQ2

blood factorsQ1

ratsQ2

Abstract

BACKGROUND: Aflatoxins are a group of mycotoxins produced by Aspergillus flavus and Aspergillus parasiticus and are an important factor in oxidative damage to the kidney and liver. OBJECTIVES: The purpose of this study was to evaluate the effects of turmeric extract and/or sodium bentonite against renal and hepatic damage induced by aflatoxin B1. METHODS: In this experiment, which lasted for four weeks, 64 male Wistar rats were randomly assigned to eight groups including: control, aflatoxin (AF), turmeric extract (TE), sodium bentonit (SB), TE+SE, AF+TE, AF+SB, AF+(TE+SB). At the end of experiment blood samples were taken from heart and some biochemical analyses were performed. RESULTS: In the AF group, the levels of alanine aminotransferase (ALT), alkaline phosphatase (ALP), low density lipoprotein (LDL) and creatinine (p<0. 05) significantly increased and uric acid numerically increased (p=0. 056) compared to control group. Treatment of AF contaminated group with TE or SB alone remarkably decreased the levels of ALT, ALP, creatinine and uric acid. TE and SB in normal rats had no significant effect on the levels of liver enzyme compared to the control group. CONCLUSIONS: According to the present research, it seems that TE and SB alone decrease the harmful effects of aflatoxin B1 and the combination of them has a potentiating effect.

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APA: Copy

Rialy, a., SARIR, H., MOJTAHEDI, M., & ABTAHI, H.. (2017). The effect of turmeric extract and sodium bentonite on some biochemical parameters in rats contaminated with Aflatoxin B1. JOURNAL OF VETERINARY RESEARCH, 72(3 ), 355-363. SID. https://sid.ir/paper/34731/en

Vancouver: Copy

Rialy a., SARIR H., MOJTAHEDI M., ABTAHI H.. The effect of turmeric extract and sodium bentonite on some biochemical parameters in rats contaminated with Aflatoxin B1. JOURNAL OF VETERINARY RESEARCH[Internet]. 2017;72(3 ):355-363. Available from: https://sid.ir/paper/34731/en

IEEE: Copy

a. Rialy, H. SARIR, M. MOJTAHEDI, and H. ABTAHI, “The effect of turmeric extract and sodium bentonite on some biochemical parameters in rats contaminated with Aflatoxin B1,” JOURNAL OF VETERINARY RESEARCH, vol. 72, no. 3 , pp. 355–363, 2017, [Online]. Available: https://sid.ir/paper/34731/en

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