In vitro Antibacterial Activity of Thymus vulgaris Essential Oil against Mycobacterium tuberculosis

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POURAZAR DIZAJI SH.; SOLEIMANI N.; AFROUGH P.; SAEDI S.

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Journal: Infection Epidemiology and Microbiology Year:2018 | Volume:4 | Issue:2 Page(s): 47-51

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Information Journal Paper

Title

In vitro Antibacterial Activity of Thymus vulgaris Essential Oil against Mycobacterium tuberculosis

Author(s)

POURAZAR DIZAJI SH. | SOLEIMANI N. | AFROUGH P. | SAEDI S. | Issue Writer Certificate

Keywords

Minimum Inhibitory Concentration

Mycobacterium tuberculosis

Antibiotic Resistance

Thymus vulgaris

Abstract

Aims Nowadays, treatment of bacterial infections is one of the most important challenges in the world. Medicinal plants offer a great hope to overcome these needs because of their chemical diversity and their significant role in the drug development. The aim of this study was to evaluate the in vitro antibacterial activity of the thyme (Thymus vulgaris) essential oil against Mycobacterium tuberculosis. Materials & Methods In this experimental study, thyme herb plants were collected and thyme essential oil was extracted. The Minimum Inhibitory Concentration (MICs) tests were performed to determine the antimicrobial activity of Thymus plant against the first (Isoniazid, Rifampicin, Ethambutol) and second (Cycloserine, Streptomycin, Kanamycin) drug antibiotics of mycobacterium. Data were analyzed by SPSS 21 software, using one-way ANOVA test. Findings The MICs for Isoniazid, Ethambutol, Streptomycin and Cycloserine were less than 10μ g/ml and the MIC values for Rifampicin and Kanamycin were 40μ g/ml. The limits of minimal inhibitory concentration of essential oil was between 0. 5-40μ g/ml (p<0. 05). Conclusion Thyme essential oil has antibacterial activity against Mycobacterium tuberclusis.

Cites

Antibacterial effects of Thymus vulgaris, Mentha pulegium, Crocus sativus and Salvia officinalis on pathogenic bacteria: A brief review study based on grampositive and gram-negative bacteria

References

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APA: Copy

POURAZAR DIZAJI, SH., SOLEIMANI, N., AFROUGH, P., & SAEDI, S.. (2018). In vitro Antibacterial Activity of Thymus vulgaris Essential Oil against Mycobacterium tuberculosis. INFECTION EPIDEMIOLOGY AND MICROBIOLOGY (INFECTION EPIDEMIOLOGY AND MEDICINE), 4(2), 47-51. SID. https://sid.ir/paper/348249/en

Vancouver: Copy

POURAZAR DIZAJI SH., SOLEIMANI N., AFROUGH P., SAEDI S.. In vitro Antibacterial Activity of Thymus vulgaris Essential Oil against Mycobacterium tuberculosis. INFECTION EPIDEMIOLOGY AND MICROBIOLOGY (INFECTION EPIDEMIOLOGY AND MEDICINE)[Internet]. 2018;4(2):47-51. Available from: https://sid.ir/paper/348249/en

IEEE: Copy

SH. POURAZAR DIZAJI, N. SOLEIMANI, P. AFROUGH, and S. SAEDI, “In vitro Antibacterial Activity of Thymus vulgaris Essential Oil against Mycobacterium tuberculosis,” INFECTION EPIDEMIOLOGY AND MICROBIOLOGY (INFECTION EPIDEMIOLOGY AND MEDICINE), vol. 4, no. 2, pp. 47–51, 2018, [Online]. Available: https://sid.ir/paper/348249/en

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