HISTOMORPHOMETRIC AND HISTOCHEMICAL STUDY OF RAT OVARY FOLLOWING IRON OXIDE AND IRON OXIDE NANOPARTICLES CONSUMPTION

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

MOROVVATI H.; NAJAFZADEH H.; POURMOUSAVI S.M.; SHAHRIARI A.; MOHAMMADIAN B.; KAZEMINEZHAD I.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Veterinary Research Year:2016 | Volume:71 | Issue:1 Page(s): 9-15

Download Full-Text

Persian Verion

View:

807

Download:

Cites:

Information Journal Paper

Title

HISTOMORPHOMETRIC AND HISTOCHEMICAL STUDY OF RAT OVARY FOLLOWING IRON OXIDE AND IRON OXIDE NANOPARTICLES CONSUMPTION

Author(s)

Keywords

FOLLICULOGENESISQ1

IRON NANOPARTICLESQ2

OVARYQ3

RATQ2

Abstract

BACKGROUND: The most common metal used in the body is iron and since it may produce ROS, it could potentially be a dangerous substance.OBJECTIVES: Regarding the side effects of nanomaterials such as nano iron particles and possibility of environmental contamination including air pollution with nanoscale iron particle, this study was designed to compare the effects of conventional iron oxide with iron oxide nanoparticles, on certain indexes of ovarian tissue in a RAT experimental model.METHODS: This animal model was carried out in 5 groups of female RATs, including control, iron oxide (15 mg) and iron oxide nanoparticles (5, 15 and 30 mg). The drugs were intraperitoneally injected daily for 16 days. On the seventeenth day the RATs were euthanized by chloroform. Ovarian tissue was removed, and histological changes and iron accumulation were assessed by special staining and light microscopy.RESULTS: According to our findings, FOLLICULOGENESIS was decreased in all groups receiving iron. The number of corpus luteum in the groups receiving different doses of nanoparticle was reduced and the number of atretic follicles was significantly increased in all groups compared to the control group.CONCLUSIONS: In conclusion, probably IRON NANOPARTICLES with impaired cellular oxidative pathways, reduces the number of follicles and corpus luteum and increase atretic follicles by producing oxygen free radicals and destructing microfilaments. This can cause a negative effect on the fertility of female RATs.

Cites

No record.

References

No record.

Cite

APA: Copy

MOROVVATI, H., NAJAFZADEH, H., POURMOUSAVI, S.M., SHAHRIARI, A., MOHAMMADIAN, B., & KAZEMINEZHAD, I.. (2016). HISTOMORPHOMETRIC AND HISTOCHEMICAL STUDY OF RAT OVARY FOLLOWING IRON OXIDE AND IRON OXIDE NANOPARTICLES CONSUMPTION. JOURNAL OF VETERINARY RESEARCH, 71(1), 9-15. SID. https://sid.ir/paper/34859/en

Vancouver: Copy

MOROVVATI H., NAJAFZADEH H., POURMOUSAVI S.M., SHAHRIARI A., MOHAMMADIAN B., KAZEMINEZHAD I.. HISTOMORPHOMETRIC AND HISTOCHEMICAL STUDY OF RAT OVARY FOLLOWING IRON OXIDE AND IRON OXIDE NANOPARTICLES CONSUMPTION. JOURNAL OF VETERINARY RESEARCH[Internet]. 2016;71(1):9-15. Available from: https://sid.ir/paper/34859/en

IEEE: Copy

H. MOROVVATI, H. NAJAFZADEH, S.M. POURMOUSAVI, A. SHAHRIARI, B. MOHAMMADIAN, and I. KAZEMINEZHAD, “HISTOMORPHOMETRIC AND HISTOCHEMICAL STUDY OF RAT OVARY FOLLOWING IRON OXIDE AND IRON OXIDE NANOPARTICLES CONSUMPTION,” JOURNAL OF VETERINARY RESEARCH, vol. 71, no. 1, pp. 9–15, 2016, [Online]. Available: https://sid.ir/paper/34859/en

Related Journal Papers