COMPARATIVE STUDY ON THE EFFECTS OF FLUNIXIN MEGLUMINE AND KETOPROFEN ON HAEMATOLOGICAL AND SOME BIOCHEMICAL PARAMETERS OF CATTLE

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NAZIFI S.; REZAKHANI A.; GHANBARI MAHARLOO F.

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Journal: Journal of Veterinary Research Year:2002 | Volume:57 | Issue:2 Page(s): 95-99

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Title

COMPARATIVE STUDY ON THE EFFECTS OF FLUNIXIN MEGLUMINE AND KETOPROFEN ON HAEMATOLOGICAL AND SOME BIOCHEMICAL PARAMETERS OF CATTLE

Author(s)

NAZIFI S. | REZAKHANI A. | GHANBARI MAHARLOO F. | Issue Writer Certificate

Keywords

FLUNIXIN MEGLUMINEQ4

KETOPROFCNQ4

HAEMATOLOGICAL AND SERUM BIOCHEMICAL PARAMETERSQ2

CATTLE.Q4

Abstract

New Page 1 Objective: To compare the effects of two non-steroidal anti inflammatory drugs (FLUNIXIN MEGLUMINE and ketoprofen) on haematological and some biochemical parameters of CATTLE. Design: Self controlled experimental study. Animals: Five clinically healthy male CATTLE.with average weight of 150:t5kg. Procedure: Blood samples were taken for 3 consecutive days after administration of equal volume of distilled water as for control. Ketoprofen (30 fig/kg BW) was given intramuscularly for 3 days. Blood samples were obtained from the first treatment day until four days after final dosage. All the CATTLE.were given 2 months rest and then blood samples were collected in a similar way as described above, before the second drug was given. FLUNIXIN MEGLUMINE (22 fig/kg BW) was injected intravenously for 5 days and blood samples were collected for 7 days starting from the first day of injection. Statistical analysis: The data were analysed statistically by analysis of variance (ANOVA). The differences between the means were statistically estimated by the Duncans test. Results: Results revealed that PCV decreased and the percentage of neutrophils and monocytes increased significantly in flunixin meglumine group (p<0.05) when compared with the ketoprofen group which showed no significant changes. In the ketoprofen group, concentration of creatinine increased significantly (p<0.05). However, in the FLUNIXIN MEGLUMINE group, concentrations of albumin, glucose, urea nitrogcn, calcium and the activity of AST decreased significantly (p<0.05) and concentrations of creatinine and total globulin increased significantly (p<0.05). Conclusion: On the basis of the results it is concluded that ketoprofen has less side effects on haematological and biochemical parameters of CATTLE.than FLUNIXIN MEGLUMINE.

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بررسی اثرات کوتاه مدت تزریق کتوپروفن بر روی چرخه فحلی و عملکرد کبد و کلیه گاوهای شیری

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APA: Copy

NAZIFI, S., REZAKHANI, A., & GHANBARI MAHARLOO, F.. (2002). COMPARATIVE STUDY ON THE EFFECTS OF FLUNIXIN MEGLUMINE AND KETOPROFEN ON HAEMATOLOGICAL AND SOME BIOCHEMICAL PARAMETERS OF CATTLE. JOURNAL OF VETERINARY RESEARCH, 57(2), 95-99. SID. https://sid.ir/paper/35011/en

Vancouver: Copy

NAZIFI S., REZAKHANI A., GHANBARI MAHARLOO F.. COMPARATIVE STUDY ON THE EFFECTS OF FLUNIXIN MEGLUMINE AND KETOPROFEN ON HAEMATOLOGICAL AND SOME BIOCHEMICAL PARAMETERS OF CATTLE. JOURNAL OF VETERINARY RESEARCH[Internet]. 2002;57(2):95-99. Available from: https://sid.ir/paper/35011/en

IEEE: Copy

S. NAZIFI, A. REZAKHANI, and F. GHANBARI MAHARLOO, “COMPARATIVE STUDY ON THE EFFECTS OF FLUNIXIN MEGLUMINE AND KETOPROFEN ON HAEMATOLOGICAL AND SOME BIOCHEMICAL PARAMETERS OF CATTLE,” JOURNAL OF VETERINARY RESEARCH, vol. 57, no. 2, pp. 95–99, 2002, [Online]. Available: https://sid.ir/paper/35011/en

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