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Information Journal Paper

Title

Brain Structure Changes Associated With Methamphetamine Abuse in Brain Magnetic Resonance Imaging

Pages

  103-108

Abstract

 Background: Amphetamines constitute a group of central nervous system stimulators with an increasing frequency of usage and destructive outcomes on the metabolism, perfusion, and structure of the brain. This study aimed at evaluating the structural brain changes following Amphetamines abuse, using Magnetic Resonance Imaging (MRI). Methods: This cross sectional study was conducted on the individuals, who were admitted to the toxicology Emergency Room (ER) with continuous Amphetamines abuse for at least six months and a positive Amphetamine/fa?page=1&sort=1&ftyp=all&fgrp=all&fyrs=all" target="_blank">MethAmphetamine urine test. Positive Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) criteria for dependency and addiction to Amphetamine/fa?page=1&sort=1&ftyp=all&fgrp=all&fyrs=all" target="_blank">MethAmphetamine were also considered as the inclusion criteria. Following informed consent, the demographic information, and data on Amphetamine/fa?page=1&sort=1&ftyp=all&fgrp=all&fyrs=all" target="_blank">MethAmphetamine use were collected. An MRI was performed for all participants as soon as relative recovery. A matched control group also underwent MRI simultaneously. Results: Forty male (20 cases of Amphetamine/fa?page=1&sort=1&ftyp=all&fgrp=all&fyrs=all" target="_blank">MethAmphetamine addicts and 20 healthy individuals) with a Mean± SD age of 28. 1± 5. 11 years were investigated. The Mean± SD age of starting Amphetamine/fa?page=1&sort=1&ftyp=all&fgrp=all&fyrs=all" target="_blank">MethAmphetamine abuse was 25. 6± 10 years. About (75%), (n=15) of the patients abused Amphetamine/fa?page=1&sort=1&ftyp=all&fgrp=all&fyrs=all" target="_blank">MethAmphetamine 6-9 months, while others had abused it for more than 10 months. All cases used to abuse Amphetamine/fa?page=1&sort=1&ftyp=all&fgrp=all&fyrs=all" target="_blank">MethAmphetamine at least once a week, with (85%) of them inhaling it. The results showed that the only change in the brain MRI of Amphetamine/fa?page=1&sort=1&ftyp=all&fgrp=all&fyrs=all" target="_blank">MethAmphetamine abusers was hyperintensities increase in deep and periventricular white matter (only positive MRI in 3 cases, P=0. 231). Oral consumption and higher doses had induced greater changes in the brain structure. Conclusion: Amphetamine/fa?page=1&sort=1&ftyp=all&fgrp=all&fyrs=all" target="_blank">MethAmphetamine dependency may increase deep and periventricular white matter hyperintensities.

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    APA: Copy

    DADPOUR, BITA, Faghani, Roya, VAHABZADEH, MARYAM, DAVOUDI, YASMIN, & NAJARI, FARES. (2019). Brain Structure Changes Associated With Methamphetamine Abuse in Brain Magnetic Resonance Imaging. INTERNATIONAL JOURNAL OF MEDICAL TOXICOLOGY AND FORENSIC MEDICINE, 9(3), 103-108. SID. https://sid.ir/paper/350689/en

    Vancouver: Copy

    DADPOUR BITA, Faghani Roya, VAHABZADEH MARYAM, DAVOUDI YASMIN, NAJARI FARES. Brain Structure Changes Associated With Methamphetamine Abuse in Brain Magnetic Resonance Imaging. INTERNATIONAL JOURNAL OF MEDICAL TOXICOLOGY AND FORENSIC MEDICINE[Internet]. 2019;9(3):103-108. Available from: https://sid.ir/paper/350689/en

    IEEE: Copy

    BITA DADPOUR, Roya Faghani, MARYAM VAHABZADEH, YASMIN DAVOUDI, and FARES NAJARI, “Brain Structure Changes Associated With Methamphetamine Abuse in Brain Magnetic Resonance Imaging,” INTERNATIONAL JOURNAL OF MEDICAL TOXICOLOGY AND FORENSIC MEDICINE, vol. 9, no. 3, pp. 103–108, 2019, [Online]. Available: https://sid.ir/paper/350689/en

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