Adipokine Omentin-1: A Diagnostic Tool in Breast Cancer

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Nourbakhsh Parisa; GANJI ALI; Farahani Iman; Hosseinian Rezvan; Yeganefard Fatemeh; MIRZAEE REZVAN; MOSAYEBI GHASEM

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: International Journal of Basic Science in Medicine Year:2018 | Volume:3 | Issue:2 Page(s): 89-93

Download Full-Text

View:

204

Download:

Cites:

Information Journal Paper

Title

Adipokine Omentin-1: A Diagnostic Tool in Breast Cancer

Author(s)

Keywords

Adipokine

Breast cancer

Omentin-1

Abstract

Introduction: Breast cancer is the most frequent solid malignancy in women. Omentin-1 is synthesized by visceral adipose tissue, placenta, and ovary and its production is altered in some cancers. The aim of this study was to assess Omentin-1 as a diagnostic marker in patients with Breast cancer. Methods: The participants of the study included 90 women (45 patients with Breast cancer and 45 healthy women as control group). In addition to anthropometric and blood parameters analysis, Omentin-1 serum levels were measured by enzyme-linked immunosorbent assays method. Receiver operator characteristic curve and positive and negative predictive values (PPV and NPV) were calculated to define diagnostic accuracy. Results: Serum Omentin-1 level in Breast cancer patients (157 ng/L ± 66 ng/L, mean ± SD) was significantly lower than that of the control group (217 ng/L ± 75 ng/L, mean ± SD). There was no significant correlation between Omentin-1 levels and anthropometric and blood parameters. The best cut-off point for the diagnosis of Breast cancer was at 146 ng/L. The sensitivity and specificity for Omentin-1 with 95% CI (0. 611 to 0. 837) were 60% and 85%, respectively. Calculated PPV and NPV at the 146 ng/L cut-off point were 88. 8% and 51. 5%, respectively. Conclusion: Breast cancer patients had significantly lower serum level of Omentin-1 than healthy women. Omentin-1 may be beneficial as a screening test along with the early-approved methods in the diagnosis of patients with Breast cancer.

Cites

An Overview of Antimicrobial Peptides as Anticancer Agents

References

Circulating levels of omentin-1 in patients with breast cancer

Cite

APA: Copy

Nourbakhsh, Parisa, GANJI, ALI, Farahani, Iman, Hosseinian, Rezvan, Yeganefard, Fatemeh, MIRZAEE, REZVAN, & MOSAYEBI, GHASEM. (2018). Adipokine Omentin-1: A Diagnostic Tool in Breast Cancer. INTERNATIONAL JOURNAL OF BASIC SCIENCE IN MEDICINE, 3(2), 89-93. SID. https://sid.ir/paper/350707/en

Vancouver: Copy

Nourbakhsh Parisa, GANJI ALI, Farahani Iman, Hosseinian Rezvan, Yeganefard Fatemeh, MIRZAEE REZVAN, MOSAYEBI GHASEM. Adipokine Omentin-1: A Diagnostic Tool in Breast Cancer. INTERNATIONAL JOURNAL OF BASIC SCIENCE IN MEDICINE[Internet]. 2018;3(2):89-93. Available from: https://sid.ir/paper/350707/en

IEEE: Copy

Parisa Nourbakhsh, ALI GANJI, Iman Farahani, Rezvan Hosseinian, Fatemeh Yeganefard, REZVAN MIRZAEE, and GHASEM MOSAYEBI, “Adipokine Omentin-1: A Diagnostic Tool in Breast Cancer,” INTERNATIONAL JOURNAL OF BASIC SCIENCE IN MEDICINE, vol. 3, no. 2, pp. 89–93, 2018, [Online]. Available: https://sid.ir/paper/350707/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops