EFFECTS OF CEYLON CINNAMON ETHANOLIC EXTRACT AND FLAXSEED OIL ON CUTANEOUS WOUNDS HEALING IN RAT

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HESARAKI S.; FARAHPOUR M.R.; YAHYAEI B.

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Paper Information

Journal: IRANIAN JOURNAL OF MEDICINAL AND AROMATIC PLANTS Year:2016 | Volume:31 | Issue:6 (74) Page(s): 1005-1112

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Title

EFFECTS OF CEYLON CINNAMON ETHANOLIC EXTRACT AND FLAXSEED OIL ON CUTANEOUS WOUNDS HEALING IN RAT

Author(s)

HESARAKI S. | FARAHPOUR M.R. | YAHYAEI B. | Issue Writer Certificate

Keywords

WOUND HEALINGQ2

CEYLON CINNAMONQ2

FLAXSEED OILQ2

EPITHELIZATIONQ2

Abstract

Wound is an inevitable event in life, occurring due to microbial infection or physical or chemical damage. The present study was conducted in order to compare the effect of CEYLON CINNAMON extract and FLAXSEED OIL on the healing of wounds induced in rat. Thirty-two rats were divided into four groups. The WOUND HEALING process was evaluated for groups related to CEYLON CINNAMON ethanolic extract (3%) and FLAXSEED OIL at a concentration of 3% on days 3, 7, 14 and 21. In addition, one group received no treatment as control, and one group received the Vaseline eucerin ointment as reference standard. The results showed that CEYLON CINNAMON extract and FLAXSEED OIL were effective in accelerating the wounds healing process and, in particular, increased EPITHELIZATION rate in the treatment groups compared to the other groups, so that the size of the wound area in the CEYLON CINNAMON group, FLAXSEED OIL group, placebo group and the control group on day 21 were calculated to be 2.6±0.4, 3.72±0.05, 5.01±0.09 and 5.3±0.07, respectively. Comparative evaluation of this study showed that CEYLON CINNAMON was more effective in accelerating the closure of wound as compared with FLAXSEED OIL.

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