COMPARISON OF THE RATE OF MU RECEPTOR GENE SINGLE NUCLEOTIDE POLYMORPHISM IN ADDICTS AND NON ADDICTS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

SHEIKHHA M.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Shahid Sadoughi University of Medical Sciences Year:2010 | Volume:18 | Issue:4 (72) Page(s): 284-291

Download Full-Text

Persian Verion

View:

4,104

Download:

Cites:

Information Journal Paper

Title

COMPARISON OF THE RATE OF MU RECEPTOR GENE SINGLE NUCLEOTIDE POLYMORPHISM IN ADDICTS AND NON ADDICTS

Author(s)

Keywords

POLYMORPHISMQ2

GENETICQ2

POLYMORPHISMQ3

SINGLE NUCLEOTIDEQ2

HEROINQ2

RECEPTORSQ2

OPIOIDQ2

MUQ2

Abstract

Introduction: The importance of scientific research in prevention of drug addiction is obvious. The main site of drug action is the brain. MU receptor is the first place of drug action. In this study, the rate of MU receptor gene SINGLE NUCLEOTIDE POLYMORPHISM (SNP) was compared in addicts and non-addicts. Methods: In this study AA, AG and AA POLYMORPHISM of MU receptor gene was investigated in 47 addicts and 30 non-addicts (controls). DNA was extracted by salting out method from peripheral blood and the PCR-Arms was performed. Results: In control group, 66.7% had AA POLYMORPHISM while 68.1% of addict group showed this POLYMORPHISM. The AG POLYMORPHISM was 30% and 27.7% in control and addict groups, respectively. The GG POLYMORPHISM was 3.3% in control and 4.3% in addict group. There were no significant differences between the two groups. Discussion: Our results indicated that there is no relationship between the MU receptor gene SNP and addiction. The other SNPs in this gene and other genes MUst be investigated. In addition, it seems that other factors such as environmental factors could play a role in addiction.

Cites

References

No record.

Cite

APA: Copy

SHEIKHHA, M.. (2010). COMPARISON OF THE RATE OF MU RECEPTOR GENE SINGLE NUCLEOTIDE POLYMORPHISM IN ADDICTS AND NON ADDICTS. JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES, 18(4 (72)), 284-291. SID. https://sid.ir/paper/35669/en

Vancouver: Copy

SHEIKHHA M.. COMPARISON OF THE RATE OF MU RECEPTOR GENE SINGLE NUCLEOTIDE POLYMORPHISM IN ADDICTS AND NON ADDICTS. JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2010;18(4 (72)):284-291. Available from: https://sid.ir/paper/35669/en

IEEE: Copy

M. SHEIKHHA, “COMPARISON OF THE RATE OF MU RECEPTOR GENE SINGLE NUCLEOTIDE POLYMORPHISM IN ADDICTS AND NON ADDICTS,” JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES, vol. 18, no. 4 (72), pp. 284–291, 2010, [Online]. Available: https://sid.ir/paper/35669/en

Related Journal Papers