EFFECTS OF ROSMARINUS OFFICINALIS L. AERIAL PARTS ESSENTIAL OIL ON INTACT MEMORY AND SCOPOLAMINE-INDUCED LEARNING DEFICITS IN RATS PERFORMING THE MORRIS WATER MAZE TASK

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

HOSSEINZADEH H.; KARIMI GH.; NOUBAKHT M.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Medicinal Plants Year:2004 | Volume:3 | Issue:12 Page(s): 68-68

Download Full-Text

Persian Verion

View:

1,201

Download:

Cites:

Information Journal Paper

Title

EFFECTS OF ROSMARINUS OFFICINALIS L. AERIAL PARTS ESSENTIAL OIL ON INTACT MEMORY AND SCOPOLAMINE-INDUCED LEARNING DEFICITS IN RATS PERFORMING THE MORRIS WATER MAZE TASK

Author(s)

HOSSEINZADEH H. | KARIMI GH. | NOUBAKHT M. | Issue Writer Certificate

Keywords

ROSMARINUS OFFICINALISQ3

MEMORYQ4

LEARNINGQ3

MORRIS WATER MAZEQ4

Abstract

In this study, the effect of ROSMARINUS OFFICINALIS aerial parts essential oil was studied on intact MEMORY and scopolamine-induced LEARNING deficits in rats performing the MORRIS WATER MAZE task. The oil was injected intraperitoneally to rats 0.5 h before training for 5 consecutive days. During the training period, four trials were carried out each day. on the 5th day of the experiment, the locomotor activity was assesed using open field test. The oil at the doses of 125-250 mg/kg decreased the latency time to find the platform. The effect of the oil was also evaluated on hyoscine (0.5 mg/kg)-induced LEARNING deficits in rats. The oil reduced the effect of hyoscine on MEMORY. In the open field activity test, the oil at the doses 125-250 mg/kg did not change locomotor activity. The higher dose of rosemary (500 mg/kg) reduced the factors of open field test. The co-administration of oil with hyocine significantly compensated the reduction of locomotor activity in hyosine group alone. On the basis of these results, the R. officinalis aerial parts essential oil improved intact MEMORY and the hyoscine impaired acquisition/performance activity. These agents can potentially be introduced as new drugs in the treatment of cognitive dysfunctions such as Alzheimer"s disease.

Cites

No record.

References

Cite

APA: Copy

HOSSEINZADEH, H., KARIMI, GH., & NOUBAKHT, M.. (2004). EFFECTS OF ROSMARINUS OFFICINALIS L. AERIAL PARTS ESSENTIAL OIL ON INTACT MEMORY AND SCOPOLAMINE-INDUCED LEARNING DEFICITS IN RATS PERFORMING THE MORRIS WATER MAZE TASK. JOURNAL OF MEDICINAL PLANTS, 3(12), 68-68. SID. https://sid.ir/paper/357633/en

Vancouver: Copy

HOSSEINZADEH H., KARIMI GH., NOUBAKHT M.. EFFECTS OF ROSMARINUS OFFICINALIS L. AERIAL PARTS ESSENTIAL OIL ON INTACT MEMORY AND SCOPOLAMINE-INDUCED LEARNING DEFICITS IN RATS PERFORMING THE MORRIS WATER MAZE TASK. JOURNAL OF MEDICINAL PLANTS[Internet]. 2004;3(12):68-68. Available from: https://sid.ir/paper/357633/en

IEEE: Copy

H. HOSSEINZADEH, GH. KARIMI, and M. NOUBAKHT, “EFFECTS OF ROSMARINUS OFFICINALIS L. AERIAL PARTS ESSENTIAL OIL ON INTACT MEMORY AND SCOPOLAMINE-INDUCED LEARNING DEFICITS IN RATS PERFORMING THE MORRIS WATER MAZE TASK,” JOURNAL OF MEDICINAL PLANTS, vol. 3, no. 12, pp. 68–68, 2004, [Online]. Available: https://sid.ir/paper/357633/en

Related Journal Papers