EVALUATION OF NEW CASES OF THALASSEMIA MAJOR FOLLOWING MINOR THALASSEMIA SCREENING PROGRAM IN ISFAHAN

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MOAFI A.R.; RAHGOZAR S.; HORFAR H.; SHIRANI B.

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Journal: JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S) Year:2004 | Volume:22 | Issue:73 Page(s): 11-14

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Title

EVALUATION OF NEW CASES OF THALASSEMIA MAJOR FOLLOWING MINOR THALASSEMIA SCREENING PROGRAM IN ISFAHAN

Author(s)

MOAFI A.R. | RAHGOZAR S. | HORFAR H. | SHIRANI B. | Issue Writer Certificate

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Abstract

Introduction. Thalassemia major is one of the most common hemoglobin disorders in the world. The geographic distribution of thalassemia has been known for many years. Diagnosis of thalassemia minor in people who want to marry with each other is the key for preventing of thalassemia major. Screening test for thalassemia minor has been started from some years ago in Iran, but there are still some new cases of major-thal syndromes annually, and we want to investigate for the cases.Methods. 54 new cases of thalassemia major, born from 1998 to 2002, referred to Saied AI Shohada Hospital, were evaluated for the etiology of thalasseinia. Results. According to these documents, 34 cases had not been screened, and except two, all of them were related to marriage before starting screening program in Isfahan. From the 20 cases that were screened, there were 10 falts negative, and one sickle-trait. From the 9 remainder cases, 5 cases refuse for prenatal diagnosis, and 3 cases that prenatal diagnosis confirm thalassemia major but refuse for abortion, and one falts negative PCR report.Discussion. According to this data, we suggest it is necessary to do close observation for laboratory unit of screening center, to extend work shop program for staff of these centers. and complement this screening program with sickle cell screening according to WHO guidelines for the control of hemoglobin disorders.

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APA: Copy

MOAFI, A.R., RAHGOZAR, S., HORFAR, H., & SHIRANI, B.. (2004). EVALUATION OF NEW CASES OF THALASSEMIA MAJOR FOLLOWING MINOR THALASSEMIA SCREENING PROGRAM IN ISFAHAN. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), 22(73), 11-14. SID. https://sid.ir/paper/357779/en

Vancouver: Copy

MOAFI A.R., RAHGOZAR S., HORFAR H., SHIRANI B.. EVALUATION OF NEW CASES OF THALASSEMIA MAJOR FOLLOWING MINOR THALASSEMIA SCREENING PROGRAM IN ISFAHAN. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S)[Internet]. 2004;22(73):11-14. Available from: https://sid.ir/paper/357779/en

IEEE: Copy

A.R. MOAFI, S. RAHGOZAR, H. HORFAR, and B. SHIRANI, “EVALUATION OF NEW CASES OF THALASSEMIA MAJOR FOLLOWING MINOR THALASSEMIA SCREENING PROGRAM IN ISFAHAN,” JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), vol. 22, no. 73, pp. 11–14, 2004, [Online]. Available: https://sid.ir/paper/357779/en

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