A REVIEW ON THREATENING EFFECTS OF GM-CSF RECOMBINANT PROTEIN (MOLGRAMOSTIM DRUG)

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

KHOZEIMEH FAEZEH; GOLESTAN NEJAD ZAHRA; YOUSEFSHAHI HAZHIR; DOOSTMOHAMMADI MOHSEN; SIFI SAEEDEH; GAVANJI SHAHIN

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Isfahan Dental School Year:2017 | Volume:12 | Issue:4 Page(s): 445-456

Download Full-Text

Persian Verion

View:

1,081

Download:

Cites:

Information Journal Paper

Title

A REVIEW ON THREATENING EFFECTS OF GM-CSF RECOMBINANT PROTEIN (MOLGRAMOSTIM DRUG)

Author(s)

Keywords

GM-CSF (GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR)Q1

REVIEWQ1

THERAPEUTICQ1

Abstract

Introduction: Synthesis of new drugs, including GM-CSF (granulocyte-macrophage colonystimulating factor), is one of the most important use of recombinant DNA technology. GM-CSF is a Molgramostim drug that is widely used in order to reduce the side effects of chemotherapy and enhance the immune system.Treatment of dental abscesses in patients undergoing chemotherapy is one of the most common uses of this drug in dentistry. In addition, GM-CSF has a key role in the treatment of mucositis in patients undergoing chemotherapy and radiotherapy of the oral area. In this REVIEW, the different uses of the recombinant molgramostim drugs in treating different diseases were evaluated.Article Explanation: In the current REVIEW paper, relevant articles were collected from ISI Web of Science and PubMed databases by using Google Scholar search engine from 1973 to 2014. The articles were analyzed for 8 months. Articles related to the effect of recombinant GM-CSF on treating disease were included in the current paper.Conclusion: The potency of GM-CSF in inducing the production of granulocytes and macrophages in vivo shows that it can clinically increase neutrophil counts and enhance the immune system subsequent to injuries inflicted by conditions such as myelodysplastic syndrome or injuries due to chemotherapeutic agents. In addition, considering the widespread THERAPEUTIC use of GM-CSF to boost the immune system, it can be introduced as an important agent for the treatment of dental abscesses in chemotherapy patients.

Cites

No record.

References

No record.

Cite

APA: Copy

KHOZEIMEH, FAEZEH, GOLESTAN NEJAD, ZAHRA, YOUSEFSHAHI, HAZHIR, DOOSTMOHAMMADI, MOHSEN, SIFI, SAEEDEH, & GAVANJI, SHAHIN. (2017). A REVIEW ON THREATENING EFFECTS OF GM-CSF RECOMBINANT PROTEIN (MOLGRAMOSTIM DRUG). JOURNAL OF ISFAHAN DENTAL SCHOOL, 12(4), 445-456. SID. https://sid.ir/paper/359047/en

Vancouver: Copy

KHOZEIMEH FAEZEH, GOLESTAN NEJAD ZAHRA, YOUSEFSHAHI HAZHIR, DOOSTMOHAMMADI MOHSEN, SIFI SAEEDEH, GAVANJI SHAHIN. A REVIEW ON THREATENING EFFECTS OF GM-CSF RECOMBINANT PROTEIN (MOLGRAMOSTIM DRUG). JOURNAL OF ISFAHAN DENTAL SCHOOL[Internet]. 2017;12(4):445-456. Available from: https://sid.ir/paper/359047/en

IEEE: Copy

FAEZEH KHOZEIMEH, ZAHRA GOLESTAN NEJAD, HAZHIR YOUSEFSHAHI, MOHSEN DOOSTMOHAMMADI, SAEEDEH SIFI, and SHAHIN GAVANJI, “A REVIEW ON THREATENING EFFECTS OF GM-CSF RECOMBINANT PROTEIN (MOLGRAMOSTIM DRUG),” JOURNAL OF ISFAHAN DENTAL SCHOOL, vol. 12, no. 4, pp. 445–456, 2017, [Online]. Available: https://sid.ir/paper/359047/en

Related Journal Papers