THE EFFECTS OF METHAMPHETAMINE ON THE DEVELOPMENT OF THE TESTES IN IMMATURE MALE RATS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

LOTFI MARZIEH; NORI ALI; KARIMI AKBAR; PILEHVARIAN ALI ASGHAR

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Shahid Sadoughi University of Medical Sciences Year:2016 | Volume:24 | Issue:3 Page(s): 222-231

Download Full-Text

Persian Verion

View:

1,412

Download:

Cites:

Information Journal Paper

Title

THE EFFECTS OF METHAMPHETAMINE ON THE DEVELOPMENT OF THE TESTES IN IMMATURE MALE RATS

Author(s)

LOTFI MARZIEH | NORI ALI | KARIMI AKBAR | PILEHVARIAN ALI ASGHAR | Issue Writer Certificate

Keywords

METHAMPHETAMINEQ1

SPERMATOGENESISQ2

TESTISQ2

RATSQ2

Abstract

Introduction: METHAMPHETAMINE (MAMP) is a central nervous system stimulant that its consumption has increased among youths. Adolescence is considered as a critical period and the reproductive organs are developing is very sensitive so that the. In this study, the effects of METHAMPHETAMINE on the development of the testes in immature male RATS were evaluated.Methods: 40 immature male Wistar RATS (35-day-old male RATS) were divided into four groups: control and the group receiving METHAMPHETAMINE: (1, 3, 5 mg/kg). The control group received saline and experimental groups received METHAMPHETAMINE for 10 days (intraperitoneally) and they were allowed to mature. Then, the RATS were dissected. Testicularb tissue was isolated and after weighing, they were prepared to be placed in formalin. The results were analyzed by ANOVA and Duncan's test.Results: Spaces created in the seminiferous tubules showed SPERMATOGENESIS disorder. The mean number of cells (spermatogonia, spermatocyte, spermatid, sperm) in the experimental groups decreased significantly than the control group (p<0.001), this reduction was dose dependent. The average weight of the testes to the body weight in the experimental groups showed no significant difference than the control group.Conclusion: Frequent consumption of METHAMPHETAMINE, even in low doses through the influence on the pituitary -gonad and the various factors involved in SPERMATOGENESIS, can disrupt the sexual maturation, which may cause reduced fertility in males.

Cites

The Effect of Methamphetamine Injection during Post-Lactation on the Ovaries of Adult Rats

References

No record.

Cite

APA: Copy

LOTFI, MARZIEH, NORI, ALI, KARIMI, AKBAR, & PILEHVARIAN, ALI ASGHAR. (2016). THE EFFECTS OF METHAMPHETAMINE ON THE DEVELOPMENT OF THE TESTES IN IMMATURE MALE RATS. JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES, 24(3), 222-231. SID. https://sid.ir/paper/35911/en

Vancouver: Copy

LOTFI MARZIEH, NORI ALI, KARIMI AKBAR, PILEHVARIAN ALI ASGHAR. THE EFFECTS OF METHAMPHETAMINE ON THE DEVELOPMENT OF THE TESTES IN IMMATURE MALE RATS. JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2016;24(3):222-231. Available from: https://sid.ir/paper/35911/en

IEEE: Copy

MARZIEH LOTFI, ALI NORI, AKBAR KARIMI, and ALI ASGHAR PILEHVARIAN, “THE EFFECTS OF METHAMPHETAMINE ON THE DEVELOPMENT OF THE TESTES IN IMMATURE MALE RATS,” JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES, vol. 24, no. 3, pp. 222–231, 2016, [Online]. Available: https://sid.ir/paper/35911/en

Related Journal Papers