EXPRESSION AND RELOCATION OF ANNEXINS IV, V IN THE OSTEOSARCOMA CELL

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

MOHITI J.; QUJOK D.; WALKER J.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Shahid Sadoughi University of Medical Sciences Year:2000 | Volume:8 | Issue:4 Page(s): 57-62

Download Full-Text

Persian Verion

View:

983

Download:

Cites:

Information Journal Paper

Title

EXPRESSION AND RELOCATION OF ANNEXINS IV, V IN THE OSTEOSARCOMA CELL

Author(s)

MOHITI J. | QUJOK D. | WALKER J. | Issue Writer Certificate

Keywords

ANNEXINSQ4

OSTEOBALSTSQ4

OSTEOSARCOMAQ4

CALCIUMQ2

Abstract

Calcium binding proteins play essential roles in human cells .One important class of CALCIUM binding proteins is the annexin family. Different functions including mitogenic signal transudation, membrane trafficking, CALCIUM regulation and inhibition of coagulation have been proposed for them. In this study, primary cultures of human osteoblasts and an OSTEOSARCOMA cell line were used to investigate the possible role of ANNEXINS in skeketal tissue. Using specific antibodies against each annexin, the expression and the location of ANNEXINS was determined and the raising of intracellular CALCIUM on the sub cellular location of ANNEXINS was also investigated. Primary cultures of human osteoblasts and the OSTEOSARCOMA cell line express ANNEXINS I, II, IV,V, and VI, On elevation of the intracellular CALCIUM concentration with the ionoshere , ionomycine , the intranuclear pools of annexin IV in 38 ±4% of cells and annexin V of 70 ±5% of cells showed relocation to the membrane within 40 seconds. Extracellular ATP also causes relocation of the intranuclear pool of annexms IV in 22 ±4% of cells and of annexin V in 38 ± 8% of the cells. The results confirm binding of these ANNEXINS to cellular membrane response to an elevation of cytosolic CALCIUM levels.

Cites

No record.

References

No record.

Cite

APA: Copy

MOHITI, J., QUJOK, D., & WALKER, J.. (2000). EXPRESSION AND RELOCATION OF ANNEXINS IV, V IN THE OSTEOSARCOMA CELL. JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES, 8(4), 57-62. SID. https://sid.ir/paper/36103/en

Vancouver: Copy

MOHITI J., QUJOK D., WALKER J.. EXPRESSION AND RELOCATION OF ANNEXINS IV, V IN THE OSTEOSARCOMA CELL. JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2000;8(4):57-62. Available from: https://sid.ir/paper/36103/en

IEEE: Copy

J. MOHITI, D. QUJOK, and J. WALKER, “EXPRESSION AND RELOCATION OF ANNEXINS IV, V IN THE OSTEOSARCOMA CELL,” JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES, vol. 8, no. 4, pp. 57–62, 2000, [Online]. Available: https://sid.ir/paper/36103/en

Related Journal Papers